Ethylene Glycol

Ethylene Glycol

SCHEMBL8575233

CC(C)(C)C(=O)OC(=O)C(C)(C)CO.OCCO

nearest known ligand 0.34

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Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 1/20 0.34
CYP4F2 P78329 1/20 0.33
CYP4A11 Q02928 1/20 0.33
PRSS1 P07477 1/20 0.33
CTSG P08311 1/20 0.33
CTRB1 P17538 1/20 0.33
CMA1 P23946 1/20 0.33
ELANE P08246 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL8575229 0.96 PRKCA (0.32) PRKCACYP4F2CYP4A11PRSS1CTSG
SCHEMBL7784846 0.95 PRKCA (0.36) PRKCACYP4F2CYP4A11PRSS1CTSG
Ethylene Glycol SCHEMBL18304638 0.93 CYP4F2 (0.36) CYP4F2CYP4A11PRSS1CTSGCTRB1
SCHEMBL273273 0.88 PRSS1 (0.38) PRKCACYP4F2CYP4A11PRSS1CTSG
SCHEMBL28357682 0.84 PRSS1 (0.38) CYP4F2CYP4A11PRSS1CTSGCTRB1
SCHEMBL28192143 0.83 PRSS1 (0.36) CYP4F2CYP4A11PRSS1CTSGCTRB1
SCHEMBL27821627 0.82 CYP4F2 (0.50) CYP4F2CYP4A11PRSS1CTSGCTRB1
SCHEMBL28305694 0.81 PRSS1 (0.35) CYP4F2CYP4A11PRSS1CTSGCTRB1
Methylene Chloride SCHEMBL28156559 0.78 ELANE (0.35) PRKCAPRSS1CTSGCTRB1CMA1
Succinic Acid SCHEMBL28472429 0.77 EGLN1 (0.41) PRSS1CTSGCTRB1CMA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5844066-A Process for the preparation of lactic acid-based polyester DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-12-01 US disclosed