Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.37 |
| ▸ | TOP1 | P11387 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14411838 | 1.00 | LMNA (0.48) | LMNAL3MBTL1TDP1PDE4AKDM4E | |
| SCHEMBL27305435 | 0.93 | PDE4A (0.54) | LMNAL3MBTL1TDP1PDE4AKDM4E | |
| SCHEMBL8838919 | 0.93 | PDE4A (0.54) | LMNAL3MBTL1TDP1PDE4AKDM4E | |
| Water SCHEMBL28205277 | 0.91 | PDE4A (0.52) | LMNAL3MBTL1TDP1PDE4AKDM4E | |
| SCHEMBL10594780 | 0.84 | LMNA (0.38) | LMNAL3MBTL1TDP1PDE4AKDM4E | |
| SCHEMBL6038229 | 0.80 | LMNA (0.48) | LMNAL3MBTL1TDP1PDE4AKDM4E | |
| SCHEMBL9707240 | 0.80 | LMNA (0.48) | LMNAL3MBTL1TDP1PDE4AKDM4E | |
| SCHEMBL18210863 | 0.80 | LMNA (0.48) | LMNAL3MBTL1TDP1PDE4AKDM4E | |
| SCHEMBL29693578 | 0.80 | LMNA (0.48) | LMNAL3MBTL1TDP1PDE4AKDM4E | |
| SCHEMBL28073064 | 0.79 | LMNA (0.42) | LMNAL3MBTL1TDP1PDE4AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998007653-A1 | CHIRAL HYDRIDE COMPLEXES | ZEELAND CHEMICALS, INC. (US) | 1998-02-26 | — | — | WO | disclosed |