Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 3/20 | 0.58 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 6/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.37 |
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.37 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23120310 | 0.87 | TGFBR1 (0.48) | TGFBR1MMECA2FOLH1NAALAD2 | |
| SCHEMBL23120316 | 0.87 | TGFBR1 (0.48) | TGFBR1MMECA2FOLH1NAALAD2 | |
| SCHEMBL16750049 | 0.84 | TGFBR1 (0.50) | TGFBR1OR51E2MMEFOLH1NAALAD2 | |
| SCHEMBL16750052 | 0.84 | TGFBR1 (0.50) | TGFBR1OR51E2MMEFOLH1NAALAD2 | |
| SCHEMBL9911356 | 0.84 | TGFBR1 (0.50) | TGFBR1OR51E2MMEFOLH1NAALAD2 | |
| SCHEMBL15855456 | 0.80 | TGFBR1 (0.44) | TGFBR1OR51E2MMEFOLH1NAALAD2 | |
| SCHEMBL31259272 | 0.80 | TGFBR1 (0.52) | TGFBR1MMECA2CA1KDM4E | |
| SCHEMBL1939496 | 0.80 | TGFBR1 (0.47) | TGFBR1OR51E2MMEFOLH1NAALAD2 | |
| SCHEMBL22731504 | 0.80 | TGFBR1 (0.47) | TGFBR1OR51E2MMEFOLH1NAALAD2 | |
| SCHEMBL1934656 | 0.80 | TGFBR1 (0.52) | TGFBR1MMEFOLH1NAALAD2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10110190-A | — | — | None | — | — | JP | disclosed |
| JP-H10110190-A | DETERGENT COMPOSITION COMPRISING IMINOBIS (2-HYDROXYMETHYLACETIC ACID) DERIVATIVE | KAO CORP | 1998-04-28 | — | — | JP | disclosed |