SCHEMBL8575539

SCHEMBL8575539

O=C(O)/C=N/S(=O)(=O)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.45
KMT2A Q03164 3/20 0.45
LMNA P02545 2/20 0.44
MAPT P10636 2/20 0.44
KDM4E B2RXH2 1/20 0.44
PPARG P37231 1/20 0.43
TSHR P16473 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
TTR P02766 1/20 0.42
HTR6 P50406 1/20 0.41
NPSR1 Q6W5P4 2/20 0.40
ESR1 P03372 1/20 0.40
HPGD P15428 1/20 0.40
MEN1 O00255 1/20 0.40
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
TLR9 Q9NR96 1/20 0.39
MMP1 P03956 1/20 0.39
MMP2 P08253 1/20 0.39
MMP9 P14780 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8575541 1.00 ALDH1A1 (0.45) ALDH1A1KMT2ALMNAMAPTKDM4E
SCHEMBL7773013 0.81 F2 (0.44) ALDH1A1KMT2ALMNAMAPTKDM4E
SCHEMBL3893799 0.79 PPARG (0.47) ALDH1A1KMT2ALMNAMAPTKDM4E
SCHEMBL14385672 0.79 PPARG (0.47) ALDH1A1KMT2ALMNAMAPTKDM4E
SCHEMBL14359654 0.79 PPARG (0.47) ALDH1A1KMT2ALMNAMAPTKDM4E
SCHEMBL12580250 0.74 ALDH1A1 (0.51) ALDH1A1KMT2ALMNAMAPTKDM4E
SCHEMBL14399470 0.74 ALDH1A1 (0.51) ALDH1A1KMT2ALMNAMAPTKDM4E
SCHEMBL12699925 0.72 ALDH1A1 (0.69) ALDH1A1KMT2ALMNAMAPTKDM4E
SCHEMBL1933484 0.72 ALDH1A1 (0.69) ALDH1A1KMT2ALMNAMAPTKDM4E
SCHEMBL11297030 0.72 KMT2A (0.54) ALDH1A1KMT2ALMNAMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5785886-A ENHANCED BLEACH PERFORMANCE LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1998-07-28 US disclosed
US-5653910-A SYNERGISTIC MIXTURE LEVER BROTHERS COMPANY, DIVISION OF CONOPCO INC. (US) 1997-08-05 US disclosed
EP-0775192-A1 BLEACHING COMPOSITIONS CONTAINING IMINE, PEROXIDE COMPOUND AND A TRANSITION METAL CATALYST UNILEVER N.V. (NL) 1997-05-28 EP disclosed
WO-1996040855-A1 BLEACHING COMPOSITIONS CONTAINING IMINE, PEROXIDE COMPOUND AND A TRANSITION METAL CATALYST UNILEVER N.V. (NL) 1996-12-19 WO disclosed
US-5463115-A Enhance bleaching action of peroxygen compounds LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1995-10-31 US disclosed
US-5413733-A Bleaching LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1995-05-09 US disclosed
EP-0446982-B1 Low-temperature bleaching compositions UNILEVER NV (NL) 1994-10-26 EP disclosed
EP-0453003-B1 Bleach catalysts and compositions containing same UNILEVER NV (NL) 1994-10-05 EP disclosed
EP-0453003-A2 Bleach catalysts and compositions containing same UNILEVER N.V. (NL) 1991-10-23 EP disclosed
EP-0446982-A2 Low-temperature bleaching compositions UNILEVER N.V. (NL) 1991-09-18 EP disclosed
US-5047163-A Low Temperature Bleaching Composition Containing A Peroxygen Compound, A Sulfonimine Oxygen Transfer Agent Activator And A! Bleach Percursor LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1991-09-10 US disclosed
US-5041232-A Inlcudes peroxygen compound and surfactant LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1991-08-20 US disclosed