Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7272706 | 0.85 | MAPT (0.43) | CYP11B1CYP11B2ALDH1A1MAPTMEN1 | |
| SCHEMBL7274756 | 0.85 | MAPT (0.43) | CYP11B1CYP11B2ALDH1A1MAPTMEN1 | |
| SCHEMBL8575966 | 0.81 | CYP11B1 (0.40) | CYP11B1CYP11B2TSHRALDH1A1LMNA | |
| SCHEMBL7281878 | 0.80 | CYP11B1 (0.46) | CYP11B1CYP11B2ALDH1A1LMNAMAPT | |
| SCHEMBL7275527 | 0.80 | CYP11B1 (0.46) | CYP11B1CYP11B2ALDH1A1LMNAMAPT | |
| SCHEMBL7275031 | 0.76 | CYP11B1 (0.42) | CYP11B1CYP11B2ALDH1A1L3MBTL1MAPT | |
| SCHEMBL7272767 | 0.76 | CYP11B1 (0.42) | CYP11B1CYP11B2ALDH1A1L3MBTL1MAPT | |
| SCHEMBL7281223 | 0.75 | CYP11B1 (0.51) | CYP11B1CYP11B2ALDH1A1LMNAMAPT | |
| SCHEMBL7281800 | 0.74 | CYP11B1 (0.42) | CYP11B1CYP11B2TSHRPDE10AALDH1A1 | |
| SCHEMBL7275043 | 0.74 | CYP11B1 (0.42) | CYP11B1CYP11B2TSHRPDE10AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852192-A | Cyclic urea derivatives, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1998-12-22 | — | — | US | disclosed |