Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TOP2A | P11388 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8575548 | 0.81 | CYP11B1 (0.46) | CYP11B1CYP11B2TSHRKDM4EALDH1A1 | |
| SCHEMBL7280294 | 0.78 | FFAR1 (0.42) | FFAR1NOS2MMP3PIK3CGPTK2 | |
| SCHEMBL7274756 | 0.69 | MAPT (0.43) | CYP11B1CYP11B2KDM4EALDH1A1 | |
| SCHEMBL7272706 | 0.69 | MAPT (0.43) | CYP11B1CYP11B2KDM4EALDH1A1 | |
| SCHEMBL8417181 | 0.67 | CYP11B1 (0.40) | CYP11B1CYP11B2TSHRKDM4EALDH1A1 | |
| Methyl 3-Phenylpropanoate SCHEMBL27447160 | 0.65 | TDP1 (0.66) | CYP11B1CYP11B2FFAR1KDM4ECA12 | |
| SCHEMBL29237344 | 0.65 | PIK3CG (0.41) | MMP3PIK3CGPTK2ALDH1A1 | |
| SCHEMBL7275527 | 0.65 | CYP11B1 (0.46) | CYP11B1CYP11B2FFAR1KDM4EALDH1A1 | |
| SCHEMBL7281878 | 0.65 | CYP11B1 (0.46) | CYP11B1CYP11B2FFAR1KDM4EALDH1A1 | |
| SCHEMBL27304027 | 0.64 | CYP11B1 (0.64) | CYP11B1CYP11B2TSHRKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852192-A | Cyclic urea derivatives, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1998-12-22 | — | — | US | disclosed |