Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.50 |
| ▸ | HTR1A | P08908 | 3/20 | 0.50 |
| ▸ | HTR2A | P28223 | 3/20 | 0.50 |
| ▸ | DRD3 | P35462 | 3/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | DRD5 | P21918 | 1/20 | 0.50 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7660501 | 0.86 | DRD2 (0.58) | DRD2HTR1AHTR2ADRD3DRD1 | |
| SCHEMBL8012789 | 0.85 | DRD2 (0.60) | DRD2HTR1AHTR2ADRD3DRD1 | |
| SCHEMBL8011291 | 0.81 | DRD2 (0.65) | DRD2HTR1AHTR2ADRD3DRD1 | |
| SCHEMBL6991321 | 0.81 | DRD2 (0.53) | DRD2HTR1AHTR2ADRD3DRD1 | |
| SCHEMBL10532482 | 0.81 | DRD2 (0.50) | DRD2HTR1AHTR2ADRD3DRD1 | |
| SCHEMBL8001944 | 0.81 | DRD2 (0.65) | DRD2HTR1AHTR2ADRD3DRD1 | |
| SCHEMBL4053722 | 0.81 | SLC18A3 (0.62) | DRD2DRD3SLC18A3SIGMAR1 | |
| SCHEMBL10556550 | 0.80 | MEN1 (0.61) | DRD2HTR1AHTR2ADRD3DRD1 | |
| SCHEMBL8001978 | 0.80 | DRD2 (0.63) | DRD2HTR1AHTR2ADRD3DRD1 | |
| SCHEMBL8207578 | 0.79 | DRD2 (0.73) | DRD2HTR1AHTR2ADRD3DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5837707-A | USEFUL IN TREATING ANXIETY, PSYCHOSIS, EPILEPSY, CONVULSIONS, AMNESIA, PARKINSON'S DISEASE | H. LUNDBECK A/S (DK) | 1998-11-17 | — | — | US | disclosed |
| US-5830896-A | PSYCHOLOGICAL DISORDERS; ANTIEPILEPIC AGENTS; ALZHEIMER'SAND PARKINSON?S DISEASE | H. LUNDBECK A/S (DK) | 1998-11-03 | — | — | US | disclosed |
| US-5684012-A | TREATMENT OF PSYCHOLOGICAL AND NEUROLOGICAL DISORDERS | H. LUNDBECK A/S (DK) | 1997-11-04 | — | — | US | disclosed |