Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | TOP1 | P11387 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8569539 | 1.00 | SCN5A (0.44) | SCN5AKCNH2ALDH1A1POLBOPRM1 | |
| SCHEMBL8565377 | 1.00 | SCN5A (0.44) | SCN5AKCNH2ALDH1A1POLBOPRM1 | |
| Hydrochloric Acid SCHEMBL8569538 | 0.99 | SCN5A (0.43) | SCN5AKCNH2ALDH1A1POLBOPRM1 | |
| Hydrochloric Acid SCHEMBL8577938 | 0.99 | SCN5A (0.43) | SCN5AKCNH2ALDH1A1POLBOPRM1 | |
| Hydrochloric Acid SCHEMBL8575905 | 0.99 | SCN5A (0.43) | SCN5AKCNH2ALDH1A1POLBOPRM1 | |
| SCHEMBL7499390 | 0.89 | SCN5A (0.45) | SCN5AKCNH2ALDH1A1POLBOPRM1 | |
| SCHEMBL5284548 | 0.89 | KCNH2 (0.37) | SCN5AKCNH2ALDH1A1KDM4EHPGD | |
| SCHEMBL5284554 | 0.89 | KCNH2 (0.37) | SCN5AKCNH2ALDH1A1KDM4EHPGD | |
| Abt-719 SCHEMBL8569278 | 0.89 | ALDH1A1 (0.46) | SCN5AKCNH2ALDH1A1POLBOPRM1 | |
| Abt-719 SCHEMBL1290350 | 0.89 | ALDH1A1 (0.46) | SCN5AKCNH2ALDH1A1POLBOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599816-A | BACTERICIDE | ABBOTT LABORATORIES (US) | 1997-02-04 | — | — | US | claimed |
| WO-1996039407-A1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-12-12 | — | — | WO | claimed |
| US-5726182-A | TREATMENT OF BACTERIAL INFECTIONS | ABBOTT LABORATORIES (US) | 1998-03-10 | — | — | US | disclosed |
| US-5599816-A | BACTERICIDE | ABBOTT LABORATORIES (US) | 1997-02-04 | — | — | US | disclosed |
| WO-1996039407-A1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-12-12 | — | — | WO | disclosed |