Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.30 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8575877 | 0.92 | SCN5A (0.36) | KCNH2SCN5A | |
| SCHEMBL5571321 | 0.83 | ALDH1A1 (0.39) | — | |
| SCHEMBL8575755 | 0.82 | KCNH2 (0.33) | KCNH2SCN5A | |
| SCHEMBL7509631 | 0.81 | PIM1 (0.35) | — | |
| SCHEMBL8569365 | 0.81 | HPGD (0.32) | ADRB2 | |
| SCHEMBL14497194 | 0.80 | ACACB (0.37) | — | |
| SCHEMBL6803943 | 0.79 | RET (0.32) | KCNH2SCN5A | |
| SCHEMBL7099200 | 0.79 | RET (0.32) | KCNH2SCN5A | |
| SCHEMBL6803945 | 0.79 | RET (0.32) | KCNH2SCN5A | |
| SCHEMBL6169430 | 0.78 | EIF2AK4 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726182-A | TREATMENT OF BACTERIAL INFECTIONS | ABBOTT LABORATORIES (US) | 1998-03-10 | — | — | US | disclosed |
| US-5599816-A | BACTERICIDE | ABBOTT LABORATORIES (US) | 1997-02-04 | — | — | US | disclosed |
| WO-1996039407-A1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-12-12 | — | — | WO | disclosed |