SCHEMBL8575853

SCHEMBL8575853

COC(=O)CN(Cc1ccccc1)C(C)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
POLB P06746 1/20 0.45
PTPN1 P18031 2/20 0.44
PTPN6 P29350 1/20 0.44
PTPN11 Q06124 1/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
TSHR P16473 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
TP53 P04637 1/20 0.42
HPGD P15428 1/20 0.42
ALDH1A1 P00352 2/20 0.41
KDM4E B2RXH2 1/20 0.41
LMNA P02545 1/20 0.41
HDAC3 O15379 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC2 Q92769 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7406040 0.84 MEN1 (0.44) MEN1KMT2APTPN1PTPN6PTPN11
SCHEMBL23673455 0.81 ATM (0.42) MEN1KMT2APOLBPTPN1PTPN6
SCHEMBL3364898 0.80 NPC1 (0.52) MEN1KMT2APOLBPTPN1PTPN6
SCHEMBL25663392 0.79 MEN1 (0.49) MEN1KMT2APOLBNPC1RAB9A
SCHEMBL6321619 0.79 MEN1 (0.49) MEN1KMT2APOLBNPC1RAB9A
SCHEMBL6321614 0.79 MEN1 (0.49) MEN1KMT2APOLBNPC1RAB9A
SCHEMBL8577501 0.79 HPGD (0.56) MEN1KMT2ARAB9ATSHRHPGD
SCHEMBL6598581 0.79 TP53 (0.49) MEN1KMT2APOLBPTPN1PTPN6
SCHEMBL1593286 0.79 TSHR (0.50) MEN1KMT2ANPC1RAB9ATSHR
SCHEMBL10453045 0.79 ABCB1 (0.50) MEN1KMT2APOLBNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998048844-A2 ION PARIS, METHOD FOR THE PRODUCTION AND USE THEREOF AS CONTRAST AGENTS SCHERING AKTIENGESELLSCHAFT (DE) 1998-11-05 WO disclosed
WO-1998013338-A1 ION PAIRS, PROCESS FOR PRODUCING THE SAME AND THEIR USE AS CONTRAST AGENTS SCHERING AKTIENGESELLSCHAFT (DE) 1998-04-02 WO disclosed