Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.43 |
| ▸ | REN | P00797 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9841003 | 0.84 | MEN1 (0.46) | MEN1KMT2ANPC1RAB9AHPGD | |
| SCHEMBL6321614 | 0.83 | MEN1 (0.49) | ABCB1MEN1KMT2AKCNA5NPC1 | |
| SCHEMBL25663392 | 0.83 | MEN1 (0.49) | ABCB1MEN1KMT2AKCNA5NPC1 | |
| SCHEMBL6321619 | 0.83 | MEN1 (0.49) | ABCB1MEN1KMT2AKCNA5NPC1 | |
| SCHEMBL14482225 | 0.79 | EPOR (0.44) | ABCB1MEN1KMT2AKCNA5NPC1 | |
| SCHEMBL28625441 | 0.79 | KMT2A (0.47) | MEN1KMT2ANPC1RAB9AHPGD | |
| SCHEMBL17275438 | 0.79 | KMT2A (0.47) | MEN1KMT2ANPC1RAB9AHPGD | |
| SCHEMBL17275437 | 0.79 | KMT2A (0.47) | MEN1KMT2ANPC1RAB9AHPGD | |
| SCHEMBL8575853 | 0.79 | MEN1 (0.47) | ABCB1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL14482223 | 0.79 | EPOR (0.44) | ABCB1MEN1KMT2AKCNA5NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288764-B1 | OPTICALLY ACTIVE ALPHA-AMINO ALDEHYDES, PROCESSES FOR THEIR PREPARATION AND THEIR USE IN THE STEREOSELECTIVE PREPARATION OF OPTICALLY ACTIVE BETA-AMINO ALCOHOLS | BAYER AG (DE) | 1990-10-24 | — | — | EP | disclosed |