SCHEMBL8575930

SCHEMBL8575930

CCc1cccc(CN(O)Cc2cccc(CC)c2)c1

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 5/20 0.46
GRIN3B O60391 5/20 0.46
GRIN1 Q05586 5/20 0.46
GRIN2A Q12879 5/20 0.46
GRIN2B Q13224 5/20 0.46
GRIN2C Q14957 5/20 0.46
GRIN3A Q8TCU5 5/20 0.46
S1PR1 P21453 5/20 0.42
TP53 P04637 1/20 0.42
BCL2 P10415 1/20 0.41
TRPA1 O75762 1/20 0.40
SIGMAR1 Q99720 2/20 0.39
MGLL Q99685 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2A6 P11509 1/20 0.39
NISCH Q9Y2I1 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl Alcohol SCHEMBL28745884 0.81 TP53 (0.55) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
Hydrogen Peroxide SCHEMBL11520377 0.81 TP53 (0.63) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL166894 0.81 TP53 (0.61) TP53BCL2TRPA1SIGMAR1MGLL
SCHEMBL13462516 0.80 ALDH1A1 (0.56) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL10778632 0.78 TAAR1 (0.50)
SCHEMBL30698368 0.78 TAAR1 (0.50)
SCHEMBL18165002 0.78 BCHE (0.53) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL7048042 0.78 TP53 (0.61) TP53MGLLCYP1A2
SCHEMBL13181462 0.78 HRH3 (0.50) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
Benzene SCHEMBL9785236 0.78 TP53 (0.67) TP53BCL2TRPA1SIGMAR1MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998002403-A1 METHOD FOR INHIBITING VINYL AROMATIC MONOMER POLYMERIZATION IN CONDENSER AND COMPRESSION SYSTEMS BETZDEARBORN INC. (US) 1998-01-22 WO disclosed
US-5396004-A Diamine, hydroxylamine BETZ LABORATORIES, INC. (US) 1995-03-07 US disclosed
EP-0594341-A1 Compositions and methods for inhibiting vinyl aromatic monomer polymerization BETZ EUROPE, INC. (US) 1994-04-27 EP disclosed
US-4840720-A ADDING PHOSPHITE AND HYDROXYLAMINE INHIBITORS BETZ LABORATORIES, INC. (US) 1989-06-20 US disclosed