Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CASR | P41180 | 1/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.40 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.40 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.40 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.40 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.40 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8578443 | 1.00 | USP2 (0.54) | USP2HTTLPAR5KDM4EALDH1A1 | |
| SCHEMBL8578597 | 1.00 | USP2 (0.54) | USP2HTTLPAR5KDM4EALDH1A1 | |
| SCHEMBL8578527 | 1.00 | USP2 (0.54) | USP2HTTLPAR5KDM4EALDH1A1 | |
| SCHEMBL8578447 | 0.94 | KDM4E (0.49) | USP2HTTLPAR5KDM4EALDH1A1 | |
| SCHEMBL8578540 | 0.92 | USP2 (0.56) | USP2HTTLPAR5KDM4EALDH1A1 | |
| SCHEMBL12886458 | 0.87 | USP2 (0.56) | USP2HTTLPAR5KDM4EALDH1A1 | |
| SCHEMBL21019381 | 0.87 | USP2 (0.61) | USP2HTTLPAR5KDM4EKMT2A | |
| SCHEMBL15393759 | 0.87 | USP2 (0.61) | USP2HTTLPAR5KDM4EKMT2A | |
| SCHEMBL8453588 | 0.86 | USP2 (0.60) | USP2HTTLPAR5KDM4EKMT2A | |
| SCHEMBL314577 | 0.84 | USP2 (0.62) | USP2HTTLPAR5KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753707-A | TREATING SKIN DISORDER, DERMATITIS, ROUGH SKIN; BARRIER FUNCTION | KAO CORPORATION (JP) | 1998-05-19 | — | — | US | disclosed |
| EP-0761644-A2 | Amide derivatives and their use in cosmetic composition | KAO CORPORATION (JP) | 1997-03-12 | — | — | EP | disclosed |