Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Carbamic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.78 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.50 |
| ▸ | LDHA | P00338 | 2/20 | 0.50 |
| ▸ | LDHB | P07195 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 5/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 4/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | THPO | P40225 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbamic Acid SCHEMBL1700994 | 1.00 | ACHE (0.78) | ACHECA2CA9CA1LMNA | |
| Carbamic Acid SCHEMBL6242520 | 1.00 | ACHE (0.78) | ACHECA2CA9CA1LMNA | |
| Carbamic Acid SCHEMBL497132 | 1.00 | — | — | |
| Carbamic Acid SCHEMBL6242522 | 1.00 | ACHE (0.78) | ACHECA2CA9CA1LMNA | |
| Carbamic Acid SCHEMBL20658763 | 0.95 | — | — | |
| Carbamic Acid SCHEMBL453944 | 0.94 | — | — | |
| Carbamic Acid SCHEMBL7077007 | 0.94 | ACHE (0.88) | ACHECA2CA9CA1LMNA | |
| Carbamic Acid SCHEMBL1356882 | 0.94 | — | — | |
| Carbamic Acid SCHEMBL11773571 | 0.94 | ACHE (0.88) | ACHECA2CA9CA1LMNA | |
| Carbamic Acid SCHEMBL49149 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-63101078-A | — | — | None | — | — | JP | disclosed |
| CN-113698657-A | Novel PU coordination substance foaming agent and preparation method thereof | 天津市红百丽科工贸有限公司 | 2021-11-26 | — | — | CN | disclosed |
| US-5824285-A | Method of making lithium manganese oxide compounds | VALENCE TECHNOLOGY, INC. (US) | 1998-10-20 | — | — | US | disclosed |
| JP-S63101078-A | WELDING METHOD FOR PIPE MATERIAL | MITSUBISHI HEAVY IND LTD | 1988-05-06 | — | — | JP | disclosed |
| US-4346082-A | Method of employing therapeutic composition comprising ammonium or substituted ammonium compounds for treatment of alcoholism | THE VINOXEN COMPANY (US) | 1982-08-24 | — | — | US | disclosed |