Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PLA2G2C | Q5R387 | 3/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5530600 | 1.00 | USP2 (0.57) | USP2HTTMEN1THRBKMT2A | |
| SCHEMBL4148593 | 0.91 | USP2 (0.48) | USP2HTTMEN1THRBKMT2A | |
| SCHEMBL314577 | 0.89 | USP2 (0.62) | USP2HTTMEN1THRBKMT2A | |
| SCHEMBL5533039 | 0.89 | USP2 (0.62) | USP2HTTMEN1THRBKMT2A | |
| SCHEMBL8457923 | 0.89 | USP2 (0.62) | USP2HTTMEN1THRBKMT2A | |
| SCHEMBL3924210 | 0.89 | USP2 (0.62) | USP2HTTMEN1THRBKMT2A | |
| SCHEMBL13269710 | 0.89 | USP2 (0.62) | USP2HTTMEN1THRBKMT2A | |
| SCHEMBL8453588 | 0.88 | USP2 (0.60) | USP2HTTMEN1THRBKMT2A | |
| SCHEMBL4791926 | 0.87 | HTT (0.58) | USP2HTTMEN1THRBKMT2A | |
| SCHEMBL15393759 | 0.86 | USP2 (0.61) | USP2HTTMEN1THRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753707-A | TREATING SKIN DISORDER, DERMATITIS, ROUGH SKIN; BARRIER FUNCTION | KAO CORPORATION (JP) | 1998-05-19 | — | — | US | disclosed |
| EP-0761644-A2 | Amide derivatives and their use in cosmetic composition | KAO CORPORATION (JP) | 1997-03-12 | — | — | EP | disclosed |