SCHEMBL5530600

SCHEMBL5530600

CCCCCCCCCCCCCCCCCOCC(O)CNCCOCCO

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.57
HTT P42858 2/20 0.54
MEN1 O00255 1/20 0.54
THRB P10828 1/20 0.54
KMT2A Q03164 1/20 0.54
MAPT P10636 1/20 0.54
TSHR P16473 1/20 0.46
LPAR5 Q9H1C0 2/20 0.46
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C19 P33261 1/20 0.43
KDM4E B2RXH2 1/20 0.42
PLA2G2C Q5R387 3/20 0.42
SPHK1 Q9NYA1 1/20 0.41
CASR P41180 1/20 0.39
ADRB2 P07550 1/20 0.37
ADRB3 P13945 1/20 0.37
TLR2 O60603 1/20 0.36
LPAR6 P43657 1/20 0.36
LPAR1 Q92633 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8577209 1.00 USP2 (0.57) USP2HTTMEN1THRBKMT2A
SCHEMBL4148593 0.91 USP2 (0.48) USP2HTTMEN1THRBKMT2A
SCHEMBL314577 0.89 USP2 (0.62) USP2HTTMEN1THRBKMT2A
SCHEMBL5533039 0.89 USP2 (0.62) USP2HTTMEN1THRBKMT2A
SCHEMBL8457923 0.89 USP2 (0.62) USP2HTTMEN1THRBKMT2A
SCHEMBL3924210 0.89 USP2 (0.62) USP2HTTMEN1THRBKMT2A
SCHEMBL13269710 0.89 USP2 (0.62) USP2HTTMEN1THRBKMT2A
SCHEMBL8453588 0.88 USP2 (0.60) USP2HTTMEN1THRBKMT2A
SCHEMBL4791926 0.87 HTT (0.58) USP2HTTMEN1THRBKMT2A
SCHEMBL15393759 0.86 USP2 (0.61) USP2HTTMEN1THRBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020250966-A1 EMULSION COMPOSITION 花王株式会社 2020-12-17 WO disclosed
US-9694076-B2 Vesicle composition KAO CORPORATION (JP) 2017-07-04 US disclosed
US-9694076-B2 Vesicle composition KAO CORPORATION (JP) 2017-07-04 US disclosed
US-20160166698-A1 VESICLE COMPOSITION KAO CORPORATION (JP) 2016-06-16 US disclosed
US-20160166698-A1 VESICLE COMPOSITION KAO CORPORATION (JP) 2016-06-16 US disclosed
US-9278059-B2 Emulsified cosmetic composition KAO CORPORATION (JP) 2016-03-08 US disclosed
US-9278059-B2 Emulsified cosmetic composition KAO CORPORATION (JP) 2016-03-08 US disclosed
EP-2692334-B1 VESICLE COMPOSITION KAO CORP (JP) 2015-11-04 EP disclosed
US-20150133550-A1 Emulsified Cosmetic Composition KAO CORPORATION (JP) 2015-05-14 US disclosed
US-20150133550-A1 Emulsified Cosmetic Composition KAO CORPORATION (JP) 2015-05-14 US disclosed
US-8586065-B2 Oil-in-water emulsified cosmetic composition KAO CORPORATION (JP) 2013-11-19 US disclosed
US-20120295989-A1 OIL-BASED COMPOSITION KAO CORPORATION (JP) 2012-11-22 US disclosed
US-20120295989-A1 OIL-BASED COMPOSITION KAO CORPORATION (JP) 2012-11-22 US disclosed
US-8178584-B2 Sphingosines, fatty acid, and oil; improved stability and feel to skin KAO CORPORATION (JP) 2012-05-15 US disclosed
US-8178584-B2 Sphingosines, fatty acid, and oil; improved stability and feel to skin KAO CORPORATION (JP) 2012-05-15 US disclosed
US-20100311836-A1 OIL-IN-WATER EMULSIFIED COSMETIC COMPOSITION KAO CORPORATION (JP) 2010-12-09 US disclosed
US-20100311836-A1 OIL-IN-WATER EMULSIFIED COSMETIC COMPOSITION KAO CORPORATION (JP) 2010-12-09 US disclosed
US-7846969-B2 Ceramide emulsions KAO CORPORATION (JP) 2010-12-07 US disclosed
US-7846969-B2 Ceramide emulsions KAO CORPORATION (JP) 2010-12-07 US disclosed
EP-1486194-B1 Oil-in-water emulsified cosmetic composition KAO CORP (JP) 2010-07-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120295989-A1 OIL-BASED COMPOSITION SGMS1, SGMS2, F12 USP2 3763/4885HTT 4324/4885MEN1 689/4885
US-20160166698-A1 VESICLE COMPOSITION SGMS1, EXOSC10, SGMS2 USP2 3794/4885HTT 4714/4885MEN1 226/4885
US-20100311836-A1 OIL-IN-WATER EMULSIFIED COSMETIC COMPOSITION CERT1, SGMS1, DEGS1 USP2 3447/4885HTT 2149/4885MEN1 565/4885
US-20150133550-A1 Emulsified Cosmetic Composition SGMS2, SGMS1, DEGS1 USP2 3859/4885HTT 3166/4885MEN1 584/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.