Urethane

Urethane

SCHEMBL8577236

CCOC(N)=O.CCOCC.OCCO

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.71
ALDH1A1 P00352 5/20 0.42
LMNA P02545 3/20 0.40
HSD17B10 Q99714 2/20 0.40
GAA P10253 2/20 0.39
MGAM O43451 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
SOAT1 P35610 1/20 0.39
TSHR P16473 2/20 0.38
CHRM2 P08172 2/20 0.37
CHRM4 P08173 2/20 0.37
CHRM5 P08912 2/20 0.37
CHRM1 P11229 2/20 0.37
CHRM3 P20309 2/20 0.37
HTR1A P08908 1/20 0.37
CHRNB2 P17787 1/20 0.37
CYP2C19 P33261 1/20 0.37
CHRNA7 P36544 1/20 0.37
CHRNA4 P43681 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urethane SCHEMBL11108306 0.93 ALOX15 (0.83) ALOX15ALDH1A1LMNAHSD17B10GAA
Urethane SCHEMBL28888854 0.93 ALOX15 (0.83) ALOX15ALDH1A1LMNAHSD17B10GAA
Urethane SCHEMBL292326 0.93 ALOX15 (0.83) ALOX15ALDH1A1LMNAHSD17B10GAA
Urethane SCHEMBL1450092 0.93 ALOX15 (0.83) ALOX15ALDH1A1LMNAHSD17B10GAA
Urethane SCHEMBL10413191 0.90 ALOX15 (0.79) ALOX15ALDH1A1LMNAHSD17B10GAA
Urethane SCHEMBL27840776 0.90 ALOX15 (0.79) ALOX15ALDH1A1LMNAHSD17B10GAA
Urethane SCHEMBL1019340 0.90 ALOX15 (0.79) ALOX15ALDH1A1LMNAHSD17B10GAA
Urethane SCHEMBL8522927 0.90 ALOX15 (0.79) ALOX15ALDH1A1LMNAHSD17B10GAA
Urethane SCHEMBL20915121 0.90 ALOX15 (0.79) ALOX15ALDH1A1LMNAHSD17B10GAA
Urethane SCHEMBL11057145 0.90 ALOX15 (0.79) ALOX15ALDH1A1LMNAHSD17B10GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4919976-A ADHERING AND CURING UNCURED EPDM TERPOLYMER, CURATIVE, AND BLOWING AGENT TO PANELS AND COOLING UNIROYAL CHEMICAL COMPANY, INC. (US) 1990-04-24 US claimed
EP-0852594-A1 POLYSILOXANE POLYURETHANE COMPOSITIONS Ameron International Corporation (US) 1998-07-15 EP disclosed
US-5760155-A PREPARED FROM POLYISOCYANATE, POLYOL, SILANOL-FUNCTIONAL SILICONE INTERMEDIATE; MOISTURE CURABLE AT ROOM TEMPERATURE AMERON INTERNATIONAL CORPORATION (US) 1998-06-02 US disclosed
WO-1997011983-A1 POLYSILOXANE POLYURETHANE COMPOSITIONS AMERON INTERNATIONAL CORPORATION (US) 1997-04-03 WO disclosed