Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | PGK1 | P00558 | 1/20 | 0.35 |
| ▸ | PGK2 | P07205 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17223191 | 0.84 | POLB (0.44) | PTPN1SMN1; SMN2POLBKCNN4TSHR | |
| SCHEMBL17493606 | 0.84 | PTPN1 (0.40) | LAP3PTPN1SMN1; SMN2POLBKCNN4 | |
| Hydrogen Peroxide SCHEMBL8609891 | 0.81 | PTPN1 (0.52) | PTPN1SMN1; SMN2POLBHDAC1TSHR | |
| SCHEMBL1556937 | 0.81 | PTPN1 (0.52) | PTPN1SMN1; SMN2POLBHDAC1TSHR | |
| SCHEMBL11039412 | 0.80 | PTPN1 (0.37) | LAP3PTPN1SMN1; SMN2POLBLMNA | |
| SCHEMBL8440827 | 0.79 | SMN1; SMN2 (0.36) | LAP3PTPN1SMN1; SMN2POLBHDAC1 | |
| SCHEMBL17169196 | 0.77 | PTPN1 (0.47) | LAP3PTPN1SMN1; SMN2POLBKCNN4 | |
| SCHEMBL5897912 | 0.76 | PTPN1 (0.39) | LAP3PTPN1SMN1; SMN2POLBKCNN4 | |
| SCHEMBL5897462 | 0.73 | PTPN1 (0.47) | LAP3PTPN1SMN1; SMN2POLBKCNN4 | |
| SCHEMBL2850979 | 0.73 | PTPN1 (0.42) | LAP3PTPN1SMN1; SMN2POLBKCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5759691-A | Phosphorus-modified coating compositions, a process for their preparation, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-06-02 | — | — | US | disclosed |
| WO-1993023050-A1 | NEW DELTA-17 AND DELTA-20 OLEFINIC AND SATURATED 17β-SUBSTITUTED-4-AZA-5α-ANDROSTAN-3-ONES AS 5α-REDUCTASE INHIBITORS | MERCK & CO., INC. (US) | 1993-11-25 | — | — | WO | disclosed |