Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.65 |
| ▸ | AXL | P30530 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.49 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8578376 | 0.84 | LOXL2 (0.65) | LOXL2AXLHRH3MTNR1AMTNR1B | |
| SCHEMBL11160135 | 0.82 | LOXL2 (0.71) | LOXL2AXLHRH3MTNR1AMTNR1B | |
| SCHEMBL867547 | 0.82 | LOXL2 (0.75) | LOXL2AXLHRH3MTNR1AMTNR1B | |
| SCHEMBL2157095 | 0.80 | LOXL2 (0.73) | LOXL2AXLHRH3MTNR1AMTNR1B | |
| SCHEMBL28379600 | 0.79 | LOXL2 (0.67) | LOXL2AXLHRH3MTNR1AMTNR1B | |
| SCHEMBL11622077 | 0.79 | LOXL2 (0.71) | LOXL2AXLHRH3MTNR1AMTNR1B | |
| SCHEMBL3507809 | 0.79 | LOXL2 (1.00) | LOXL2AXLHRH3MTNR1AMTNR1B | |
| SCHEMBL31065503 | 0.79 | LOXL2 (0.62) | LOXL2PDGFRBPDGFRAKDM4ENPC1 | |
| SCHEMBL7952644 | 0.78 | LOXL2 (0.69) | LOXL2AXLHRH3MTNR1AMTNR1B | |
| SCHEMBL15902409 | 0.76 | LOXL2 (0.67) | LOXL2AXLHRH3MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118496254-A | Preparation method of silicon-containing six-membered heterocyclic compound | 五邑大学 | 2024-08-16 | — | — | CN | disclosed |
| US-5721347-A | Esters and amides of substituted pyrrole acetic acids | CELL PATHWAYS, INC. (US) | 1998-02-24 | — | — | US | disclosed |
| EP-0485157-A2 | Esters and amides of substituted pyrrole acetic acids | FGN, INC. (US) | 1992-05-13 | — | — | EP | disclosed |