SCHEMBL8577754

SCHEMBL8577754

Cn1c(=O)c2c(nc(Cc3ccccc3)n2CCNCCO)n(C)c1=O

nearest known ligand 0.63

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 1/20 0.63
PCSK9 Q8NBP7 1/20 0.61
LMNA P02545 5/20 0.60
SMN1; SMN2 Q16637 4/20 0.60
MEN1 O00255 2/20 0.60
KMT2A Q03164 2/20 0.60
MAPK1 P28482 2/20 0.60
ALDH1A1 P00352 1/20 0.56
TSHR P16473 4/20 0.53
HTT P42858 3/20 0.53
NPSR1 Q6W5P4 1/20 0.53
JAK2 O60674 1/20 0.53
ALOX15 P16050 2/20 0.52
HSD17B10 Q99714 2/20 0.52
MAPT P10636 2/20 0.51
USP2 O75604 1/20 0.51
TP53 P04637 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29377329 0.89 RXFP1 (0.66) RXFP1LMNASMN1; SMN2MEN1KMT2A
SCHEMBL8684142 0.83 RXFP1 (0.57) RXFP1PCSK9LMNASMN1; SMN2MEN1
SCHEMBL8373802 0.82 RXFP1 (0.72) RXFP1LMNASMN1; SMN2MEN1KMT2A
SCHEMBL29376542 0.82 RXFP1 (0.72) RXFP1LMNASMN1; SMN2MEN1KMT2A
Bamifylline SCHEMBL219043 0.80 RXFP1 (0.60) RXFP1LMNASMN1; SMN2MEN1KMT2A
Bamifylline SCHEMBL637064 0.79 RXFP1 (0.58) RXFP1PCSK9LMNASMN1; SMN2MEN1
SCHEMBL29375225 0.79 ALDH1A1 (0.56) RXFP1PCSK9LMNASMN1; SMN2KMT2A
Bamifylline SCHEMBL1648640 0.79 RXFP1 (0.57) RXFP1PCSK9LMNASMN1; SMN2MEN1
SCHEMBL3099603 0.78 RXFP1 (1.00) RXFP1LMNASMN1; SMN2KMT2ATSHR
SCHEMBL683954 0.78 RXFP1 (0.66) RXFP1LMNASMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250290128-A1 METHOD OF MEASURING MICROSATELLITE LENGTH VARIATIONS COLD SPRING HARBOR LABORATORY (US) 2025-09-18 US disclosed
US-12260815-B2 Display panel and display device for prolonging lifespans of pixels CHENGDU BOE OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) 2025-03-25 US disclosed
US-12192087-B2 Network distribution method and system HUAWEI TECHNOLOGIES CO., LTD. (CN) 2025-01-07 US disclosed
US-20240296791-A1 Display Panel and Display Device CHENGDU BOE OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) 2024-09-05 US disclosed
CN-111343615-B Method and apparatus for short-range communication 华为技术有限公司 2024-04-09 CN disclosed
CN-114095918-B Network distribution method and system 华为技术有限公司 2023-10-13 CN disclosed
CN-116405215-A Method and equipment for private line communication of people 偶书源 2023-07-07 CN disclosed
US-20230155914-A1 NETWORK DISTRIBUTION METHOD AND SYSTEM HUAWEI TECHNOLOGIES CO., LTD. (CN) 2023-05-18 US disclosed
EP-4181552-A1 NETWORK DISTRIBUTION METHOD AND SYSTEM Huawei Technologies Co., Ltd. (CN) 2023-05-17 EP disclosed
CN-114095918-A Network distribution method and system 华为技术有限公司 2022-02-25 CN disclosed
WO-2022022420-A1 NETWORK DISTRIBUTION METHOD AND SYSTEM 华为技术有限公司 2022-02-03 WO disclosed
US-5773306-A BINDING AN ADENOSINE RECEIVER TO SUBSTRATE; DISPLACEMENT WITH ENDOTOXIN TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 1998-06-30 US disclosed