Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | HTT | P42858 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | GLA | P06280 | 2/20 | 0.69 |
| ▸ | HPGD | P15428 | 2/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | ATM | Q13315 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | CASP6 | P55212 | 1/20 | 0.61 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.60 |
| ▸ | CTSV | O60911 | 3/20 | 0.54 |
| ▸ | CTSL | P07711 | 3/20 | 0.54 |
| ▸ | AHR | P35869 | 1/20 | 0.52 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22875997 | 0.92 | PDE3B (0.58) | GAAALDH1A1HTTKDM4EGLA | |
| Naphthalene SCHEMBL28078626 | 0.90 | GAA (0.72) | GAAALDH1A1HTTKDM4EGLA | |
| SCHEMBL13412897 | 0.90 | PDE3B (0.56) | GAAALDH1A1HTTKDM4EGLA | |
| SCHEMBL13412901 | 0.88 | GAA (0.82) | GAAALDH1A1HTTKDM4EGLA | |
| SCHEMBL22367061 | 0.88 | GAA (0.82) | GAAALDH1A1HTTKDM4EGLA | |
| SCHEMBL29349876 | 0.88 | GAA (0.82) | GAAALDH1A1HTTKDM4EGLA | |
| SCHEMBL92077 | 0.88 | GAA (0.82) | GAAALDH1A1HTTKDM4EGLA | |
| SCHEMBL2630573 | 0.86 | GAA (0.78) | GAAALDH1A1HTTKDM4EGLA | |
| SCHEMBL31037120 | 0.84 | AHR (0.74) | ALDH1A1KDM4EHPGDATMMEN1 | |
| SCHEMBL29386574 | 0.84 | AHR (0.74) | ALDH1A1KDM4EHPGDATMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10237440-A | — | — | None | — | — | JP | disclosed |
| JP-H10237440-A | ORGANIC ELECTROLUMINESCENT ELEMENT | MITSUI CHEM INC | 1998-09-08 | — | — | JP | disclosed |
| EP-0369344-B1 | N-arylation of isatins | ABBOTT LAB (US) | 1994-04-06 | — | — | EP | disclosed |
| EP-0369344-A1 | N-arylation of isatins | ABBOTT LABORATORIES (US) | 1990-05-23 | — | — | EP | disclosed |
| US-3968051-A | VINYL RESIN, POLYAROMATIC MATERIAL | AMERICAN CYANAMID COMPANY (US) | 1976-07-06 | — | — | US | disclosed |