SCHEMBL8577895

SCHEMBL8577895

CCOC(=O)C(=Cc1ccc(-c2ccccc2)cc1)C(=O)OCC

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.84
KMT2A Q03164 7/20 0.84
MAPT P10636 9/20 0.67
LMNA P02545 4/20 0.67
NPSR1 Q6W5P4 3/20 0.67
CYP1A2 P05177 1/20 0.67
CYP2C9 P11712 1/20 0.67
CYP2C19 P33261 1/20 0.67
S1PR4 O95977 1/20 0.67
S1PR1 P21453 1/20 0.67
MAPK1 P28482 1/20 0.67
NR1H4 Q96RI1 1/20 0.66
TP53 P04637 1/20 0.59
KDM4E B2RXH2 2/20 0.58
ALDH1A1 P00352 2/20 0.58
HSP90AA1 P07900 2/20 0.58
HPGD P15428 1/20 0.58
DHODH Q02127 2/20 0.55
SMN1; SMN2 Q16637 3/20 0.54
CRHBP P24387 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL935186 0.92 MEN1 (1.00) MEN1KMT2AMAPTLMNANPSR1
Benzene SCHEMBL27988126 0.92 MEN1 (1.00) MEN1KMT2AMAPTLMNANPSR1
Butane SCHEMBL6828046 0.88 MEN1 (0.93) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL1068265 0.88 MEN1 (0.85) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL27872595 0.87 MEN1 (0.90) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL14432387 0.87 MEN1 (0.90) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL2411174 0.87 MEN1 (0.90) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL7273126 0.85 KMT2A (0.87) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL9726815 0.85 MEN1 (0.87) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL12913257 0.85 KMT2A (0.87) MEN1KMT2AMAPTLMNANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5705545-A HINDERED AMINE LIGHT STABILIZER COMPOUND FOR THERMOPLASTIC POLYMERS CLARIANT FINANCE (BVI) LIMITED (VG) 1998-01-06 US disclosed
EP-0141140-B1 BENZYLIDENE MALONIC ACID POLYESTERS, PROCESS FOR THEIR PREPARATION AND THE USE OF SUCH POLYESTERS IN THE STABILISATION OF THERMOPLASTIC RESINS AGAINST U.V. BAYER AG (DE) 1987-01-21 EP disclosed
US-4588807-A ANTIASTHMA, ANTIULCERE, ANTICOAGULANT BAYER AKTIENGESELLSCHAFT (DE) 1986-05-13 US disclosed
EP-0141140-A1 Benzylidene malonic acid polyesters, process for their preparation and the use of such polyesters in the stabilisation of thermoplastic resins against U.V. BAYER AG (DE) 1985-05-15 EP disclosed
US-4228067-A UV Light stabilized polycarbonate composition BAYER AKTIENGESELLSCHAFT (DE) 1980-10-14 US disclosed