Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | G6PD | P11413 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8575326 | 0.90 | TSHR (0.49) | KDM4EMAPTNPC1P2RX7TP53 | |
| SCHEMBL8577820 | 0.87 | HTT (0.43) | KDM4EMAPTMAPK1DAOTP53 | |
| SCHEMBL8576994 | 0.81 | MEN1 (0.52) | KDM4EMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL8579589 | 0.80 | KMT2A (0.45) | KDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL8577000 | 0.76 | MEN1 (0.47) | KDM4EMAPTNPC1P2RX7TP53 | |
| SCHEMBL8579118 | 0.75 | DAO (0.58) | KDM4EMAPTG6PDNPC1MAPK1 | |
| SCHEMBL8576798 | 0.71 | DAO (0.53) | KDM4EMAPTG6PDNPC1MAPK1 | |
| SCHEMBL9402327 | 0.70 | ADORA2A (0.44) | KDM4EMAPTNPC1TP53RAB9A | |
| SCHEMBL8577647 | 0.69 | DAO (0.52) | KDM4EMAPTG6PDNPC1MAPK1 | |
| SCHEMBL8579120 | 0.67 | ADORA1 (0.64) | KDM4EMAPTG6PDNPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719279-A | CHOLINOMIMETICS | BOEHRINGER INGELHEIM KG (DE) | 1998-02-17 | — | — | US | disclosed |