Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 2/20 | 0.34 |
| ▸ | RARA | P10276 | 1/20 | 0.34 |
| ▸ | RARG | P13631 | 1/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.33 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 4/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 2/20 | 0.30 |
| ▸ | CNR1 | P21554 | 2/20 | 0.30 |
| ▸ | HTR1A | P08908 | 2/20 | 0.30 |
| ▸ | DRD2 | P14416 | 2/20 | 0.30 |
| ▸ | DRD1 | P21728 | 2/20 | 0.30 |
| ▸ | DRD4 | P21917 | 2/20 | 0.30 |
| ▸ | DRD5 | P21918 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8580118 | 1.00 | RARB (0.34) | RARBRARARARGSPHK1P2RY14 | |
| SCHEMBL8579023 | 0.99 | RARB (0.32) | RARBRARARARGSPHK1P2RY14 | |
| SCHEMBL8580088 | 0.91 | AKR1C2 (0.34) | AKR1C2AKR1C1NPC1RAB9AESR2 | |
| SCHEMBL8580084 | 0.91 | AKR1C2 (0.34) | AKR1C2AKR1C1NPC1RAB9AESR2 | |
| SCHEMBL8578393 | 0.89 | AKR1C2 (0.33) | AKR1C2AKR1C1NPC1RAB9A | |
| SCHEMBL7751081 | 0.89 | DRD5 (0.32) | SLC18A3LMNAHTR1ADRD2DRD1 | |
| SCHEMBL8581098 | 0.87 | ESR2 (0.36) | SPHK1NPC1RAB9AESR2 | |
| SCHEMBL8635150 | 0.86 | APP (0.32) | AKR1C2AKR1C1NPC1RAB9A | |
| SCHEMBL7757549 | 0.86 | SPHK1 (0.33) | SPHK1NPC1RAB9ASLC18A3DRD2 | |
| SCHEMBL8027799 | 0.83 | SPHK1 (0.37) | SPHK1SLC18A3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5730902-A | Optically active silacyclohexane compounds, liquid crystal compositions comprising the same and liquid crystal display devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1998-03-24 | — | — | US | disclosed |
| EP-0761674-A1 | Optically active silacyclohexane compounds, liquid crystal compositions comprising the same and liquid crystal display devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-03-12 | — | — | EP | disclosed |