Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | FPR2 | P25090 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8606832 | 0.92 | POLB (0.56) | SMN1; SMN2FPR2POLBMAPT | |
| SCHEMBL8579115 | 0.86 | NPC1 (0.55) | SMN1; SMN2POLBKMT2AALDH1A1 | |
| SCHEMBL8578113 | 0.83 | CNR1 (0.56) | SMN1; SMN2FPR2MAPTCNR1KMT2A | |
| SCHEMBL8577049 | 0.83 | CNR1 (0.50) | FPR2POLBCNR1KMT2AALDH1A1 | |
| SCHEMBL30858767 | 0.82 | SMN1; SMN2 (0.77) | SMN1; SMN2FPR2CNR1GLAKMT2A | |
| SCHEMBL16562224 | 0.79 | ALDH1A1 (0.66) | SMN1; SMN2FPR2MAPTCNR1GLA | |
| SCHEMBL6317352 | 0.79 | MCL1 (0.64) | SMN1; SMN2POLBKMT2AALDH1A1LMNA | |
| SCHEMBL7025629 | 0.79 | MCL1 (0.64) | SMN1; SMN2POLBKMT2AALDH1A1LMNA | |
| SCHEMBL17790723 | 0.78 | SMN1; SMN2 (0.71) | SMN1; SMN2FPR2CNR1GLAKMT2A | |
| SCHEMBL12773610 | 0.78 | SMN1; SMN2 (0.75) | SMN1; SMN2POLBGLAKMT2APTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719279-A | CHOLINOMIMETICS | BOEHRINGER INGELHEIM KG (DE) | 1998-02-17 | — | — | US | disclosed |