Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7046377 | 0.76 | ALDH1A1 (0.40) | ALDH1A1NPSR1GLO1LMNAHSD17B10 | |
| SCHEMBL247694 | 0.75 | ALDH1A1 (0.56) | ALDH1A1NPSR1GLO1LMNAHSD17B10 | |
| SCHEMBL1418707 | 0.75 | ALDH1A1 (0.56) | ALDH1A1NPSR1GLO1LMNAHSD17B10 | |
| SCHEMBL18979198 | 0.73 | ALDH1A1 (0.53) | ALDH1A1NPSR1GLO1LMNAHSD17B10 | |
| SCHEMBL29896398 | 0.73 | ALDH1A1 (0.53) | ALDH1A1NPSR1GLO1LMNAHSD17B10 | |
| Water SCHEMBL1097795 | 0.73 | ALDH1A1 (0.53) | ALDH1A1NPSR1GLO1LMNAHSD17B10 | |
| SCHEMBL6383219 | 0.72 | ALDH1A1 (0.46) | ALDH1A1LMNAHSD17B10TSHRALOX15 | |
| SCHEMBL3853357 | 0.72 | ALDH1A1 (0.46) | ALDH1A1NPSR1GLO1LMNAHSD17B10 | |
| Ammonia Solution, Strong SCHEMBL20957487 | 0.70 | CYP4F2 (0.44) | ALDH1A1LMNAHSD17B10TSHRALOX15 | |
| SCHEMBL20691515 | 0.70 | ALDH1A1 (0.43) | ALDH1A1NPSR1GLO1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808067-A | Process for preparing pyridine and quinoline derivatives | HOECHST CELANESE CORPORATION (US) | 1998-09-15 | — | — | US | claimed |
| US-5322948-A | Reacting unsaturated diacid or derivative with hydroxylamine or a salt thereof to form N-hydroxy-2-aminobutane diacid derivative | HOECHST CELANESE CORPORATION (US) | 1994-06-21 | — | — | US | claimed |
| EP-0511446-A2 | Process for preparing pyridinecarboxylic acid derivatives | HOECHST CELANESE CORPORATION (US) | 1992-11-04 | — | — | EP | claimed |
| EP-0452094-A2 | A method of the preparation of N-hydroxy aspartic acid derivate | HOECHST CELANESE CORPORATION (US) | 1991-10-16 | — | — | EP | claimed |