Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | LAP3 | P28838 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.41 |
| ▸ | PSAT1 | Q9Y617 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8580037 | 0.86 | LTA4H (0.54) | LTA4HMME | |
| SCHEMBL8581213 | 0.86 | LTA4H (0.54) | LTA4HMME | |
| SCHEMBL10198479 | 0.86 | LTA4H (0.54) | LTA4HMME | |
| SCHEMBL2873427 | 0.86 | LTA4H (0.54) | LTA4HMME | |
| SCHEMBL539481 | 0.86 | PPARG (0.52) | PPARGPPARAMMEPOLBHDAC1 | |
| Hydrochloric Acid SCHEMBL2873425 | 0.85 | LTA4H (0.53) | LTA4HMME | |
| Hydrochloric Acid SCHEMBL2873423 | 0.85 | LTA4H (0.53) | LTA4HMME | |
| Hydrochloric Acid SCHEMBL539480 | 0.85 | PPARG (0.51) | PPARGPPARAMMEPOLBHDAC1 | |
| Hydrochloric Acid SCHEMBL539482 | 0.85 | PPARG (0.51) | PPARGPPARAMMEPOLBHDAC1 | |
| SCHEMBL8174333 | 0.78 | LTA4H (0.77) | LTA4HHSD17B10LAP3ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012065958-A1 | METHOD OF TREATING CONTRAST-INDUCED NEPHROPATHY | NOVARTIS AG (CH) | 2012-05-24 | — | — | WO | disclosed |