Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 17/20 | 0.77 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.74 |
| ▸ | FNTA | P49354 | 3/20 | 0.69 |
| ▸ | FNTB | P49356 | 3/20 | 0.69 |
| ▸ | PTAFR | P25105 | 2/20 | 0.68 |
| ▸ | SLC6A15 | Q9H2J7 | 2/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29626603 | 0.93 | HRH1 (0.72) | HRH1KCNH2FNTAFNTBSLC6A15 | |
| SCHEMBL23303356 | 0.93 | HRH1 (0.72) | HRH1KCNH2FNTAFNTBSLC6A15 | |
| SCHEMBL8879606 | 0.90 | HRH1 (0.69) | HRH1KCNH2FNTAFNTBPTAFR | |
| SCHEMBL20952209 | 0.87 | HRH1 (0.80) | HRH1FNTAFNTBPTAFRSLC6A15 | |
| SCHEMBL10123931 | 0.87 | HRH1 (1.00) | HRH1KCNH2FNTAFNTBPTAFR | |
| SCHEMBL20951899 | 0.86 | HRH1 (0.79) | HRH1FNTAFNTBPTAFRSLC6A15 | |
| SCHEMBL4460572 | 0.86 | HRH1 (0.82) | HRH1KCNH2FNTAFNTBPTAFR | |
| SCHEMBL29626502 | 0.86 | HRH1 (0.82) | HRH1KCNH2FNTAFNTBPTAFR | |
| SCHEMBL31384618 | 0.86 | HRH1 (0.82) | HRH1KCNH2FNTAFNTBPTAFR | |
| SCHEMBL30758820 | 0.86 | HRH1 (0.75) | HRH1KCNH2FNTAFNTBPTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753671-A | Imidazopyridine derivatives as dual histamine (H1) and platelet activating factor (PAF) antagonists | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1998-05-19 | — | — | US | disclosed |