Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 4/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL123613 | 0.96 | APOBEC3A (0.47) | APOBEC3AAPOBEC3GALDH1A1TDP1KDM4E | |
| Bromide SCHEMBL130138 | 0.96 | APOBEC3A (0.47) | APOBEC3AAPOBEC3GALDH1A1TDP1LMNA | |
| SCHEMBL414301 | 0.93 | APOBEC3A (0.50) | APOBEC3AAPOBEC3GALDH1A1TDP1LMNA | |
| Water SCHEMBL187879 | 0.89 | APOBEC3A (0.47) | APOBEC3AAPOBEC3GALDH1A1TDP1LMNA | |
| Iodide SCHEMBL2899228 | 0.89 | APOBEC3A (0.56) | APOBEC3AAPOBEC3GALDH1A1TDP1LMNA | |
| Fluoride Ion SCHEMBL2481380 | 0.89 | APOBEC3A (0.47) | APOBEC3AAPOBEC3GALDH1A1TDP1LMNA | |
| Methane SCHEMBL27907628 | 0.89 | APOBEC3A (0.47) | APOBEC3AAPOBEC3GALDH1A1TDP1LMNA | |
| SCHEMBL12762124 | 0.89 | APOBEC3A (0.47) | APOBEC3AAPOBEC3GALDH1A1TDP1LMNA | |
| SCHEMBL6238199 | 0.83 | APOBEC3A (0.43) | APOBEC3AAPOBEC3GALDH1A1TDP1LMNA | |
| SCHEMBL7639777 | 0.80 | APOBEC3A (0.41) | APOBEC3AAPOBEC3GALDH1A1TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856520-A | OPTICAL RECORDING MEDIA | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1999-01-05 | — | — | US | disclosed |