Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL8580336 | 0.96 | APOBEC3A (0.45) | APOBEC3AAPOBEC3GALDH1A1TSHRTDP1 | |
| SCHEMBL414301 | 0.96 | APOBEC3A (0.50) | APOBEC3AAPOBEC3GALDH1A1TSHRTDP1 | |
| Water SCHEMBL187879 | 0.92 | APOBEC3A (0.47) | APOBEC3AAPOBEC3GALDH1A1TSHRTDP1 | |
| SCHEMBL12762124 | 0.92 | APOBEC3A (0.47) | APOBEC3AAPOBEC3GALDH1A1TSHRTDP1 | |
| Methane SCHEMBL27907628 | 0.92 | APOBEC3A (0.47) | APOBEC3AAPOBEC3GALDH1A1TSHRTDP1 | |
| Fluoride Ion SCHEMBL2481380 | 0.92 | APOBEC3A (0.47) | APOBEC3AAPOBEC3GALDH1A1TSHRTDP1 | |
| Iodide SCHEMBL2899228 | 0.92 | APOBEC3A (0.56) | APOBEC3AAPOBEC3GALDH1A1TSHRTDP1 | |
| Hydrochloric Acid SCHEMBL123613 | 0.92 | APOBEC3A (0.47) | APOBEC3AAPOBEC3GALDH1A1TSHRTDP1 | |
| SCHEMBL6238199 | 0.86 | APOBEC3A (0.43) | APOBEC3AAPOBEC3GALDH1A1TSHRTDP1 | |
| SCHEMBL7639777 | 0.83 | APOBEC3A (0.41) | APOBEC3AAPOBEC3GALDH1A1TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 343 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119504843-A | Quinoxaline-5-carboxylic acid coordinated catalyst, composite catalyst, preparation method and application | 上海元革新材料科技有限公司 | 2025-02-25 | — | — | CN | claimed |
| CN-117229307-A | Preparation method of tri (trimethylsilane) borate | 杉杉新材料（衢州）有限公司 | 2023-12-15 | — | — | CN | claimed |
| CN-114685274-A | Esterification method for preparing 4-methyl chloroacetoacetate | 江西迪赛诺制药有限公司 | 2022-07-01 | — | — | CN | claimed |
| CN-111763320-B | Optical resin monomer and preparation method thereof, optical resin and preparation method thereof | 山东益丰生化环保股份有限公司 | 2021-09-10 | — | — | CN | claimed |
| CN-109503693-B | Process for synthesizing Aramchol by using cholic acid as raw material | 合肥工业大学 | 2021-04-06 | — | — | CN | claimed |
| CN-111763320-A | Optical resin monomer and preparation method thereof, optical resin and preparation method thereof | 山东益丰生化环保股份有限公司 | 2020-10-13 | — | — | CN | claimed |
| EP-1659127-B1 | Preparation of sulfide chain-bearing organosilicon compounds | SHINETSU CHEMICAL CO (JP) | 2011-09-28 | — | — | EP | claimed |
| EP-1661902-B1 | Preparation of sulfide chain-bearing organosilicon compounds | SHINETSU CHEMICAL CO (JP) | 2010-03-31 | — | — | EP | claimed |
| EP-1453774-B1 | METHOD FOR THE ARYLATION OF OLEFINS | SALTIGO GMBH (DE) | 2009-01-21 | — | — | EP | claimed |
| US-7355059-B2 | Preparation of sulfide chain-bearing organosilicon compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2008-04-08 | — | — | US | claimed |
| US-20030105353-A1 | Process for the arylation of olefins | LANXESS DEUTSCHLAND GMBH (DE) | 2003-06-05 | — | — | US | claimed |
| EP-1144990-A1 | A REFERENCE ELECTRODE SOLUTION CONTAINING ORGANIC AMMONIUM AND PHOSPHONIUM SALTS FOR POTENTIOMETRIC MEASUREMENT OF pH | BAXTER INTERNATIONAL INC. (US) | 2001-10-17 | — | — | EP | claimed |
| WO-2000033064-A9 | A REFERENCE ELECTRODE SOLUTION CONTAINING ORGANIC AMMONIUM AND PHOSPHONIUM SALTS FOR POTENTIOMETRIC MEASUREMENT OF pH | BAXTER INT (US) | 2001-03-29 | — | — | WO | claimed |
| US-6143457-A | COMPRISING MIXTURE OF COLORANT AND SULFONATED POLYESTER RENDERED HYDROPHOBIC BY SALT FORMATION OF SURFACE SULFONATE GROUPS WITH QUATERNARY COMPOUND; TRIBOELECTRIC CHARGING | XEROX CORPORATION (US) | 2000-11-07 | — | — | US | claimed |
| WO-2000033064-A1 | A REFERENCE ELECTRODE SOLUTION CONTAINING ORGANIC AMMONIUM AND PHOSPHONIUM SALTS FOR POTENTIOMETRIC MEASUREMENT OF pH | BAXTER INTERNATIONAL INC. (US) | 2000-06-08 | — | — | WO | claimed |
| US-5658671-A | ARTICLE COATED WITH COMPOSITION COMPRISING FLUOROELASTOMER, QUATERNARY AMMONIUM OR PHOSPHONIUM ACCELERATOR, POLYOL, ACID ACCEPTOR, OIL-SOLUBLE CHELATING AGENT, ORGANIC SOLVENT | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-08-19 | — | — | US | claimed |
| US-5451625-A | FOR USE IN THE PREPARATION OF AUTOMOTIVE GASKETS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-09-19 | — | — | US | claimed |
| EP-0574319-A1 | Fluoroelastomer coating composition | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-12-15 | — | — | EP | claimed |
| US-5066373-A | Hydrogen electrode, double junction reference electrode with quaternary ammonium salt in outer shell | ALLIED-SIGNAL INC. (US) | 1991-11-19 | — | — | US | claimed |
| US-4069384-A | CYCLIC ANHYDRIDE; QUATERNARY AMMONIUM SALTS OR HALOGEN ACID SALTS AS CATALYSTS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1978-01-17 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105353-A1 | Process for the arylation of olefins | NEK6, JUN, AOC2 | ACHE 4596/4885APOBEC3A 550/4885APOBEC3G 607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.