Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 11/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 4/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.46 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL8460539 | 1.00 | LMNA (1.00) | LMNATSHRALDH1A1HSD17B10FGFR4 | |
| Acrylic Acid SCHEMBL5065665 | 1.00 | LMNA (1.00) | LMNATSHRALDH1A1HSD17B10FGFR4 | |
| Acrylic Acid SCHEMBL10482239 | 1.00 | LMNA (1.00) | LMNATSHRALDH1A1HSD17B10FGFR4 | |
| Acrylic Acid SCHEMBL11652408 | 1.00 | LMNA (1.00) | LMNATSHRALDH1A1HSD17B10FGFR4 | |
| Acrylic Acid SCHEMBL7706117 | 1.00 | LMNA (1.00) | LMNATSHRALDH1A1HSD17B10FGFR4 | |
| Acrylic Acid SCHEMBL8085498 | 1.00 | — | — | |
| Acrylic Acid SCHEMBL119206 | 1.00 | LMNA (1.00) | LMNATSHRALDH1A1HSD17B10FGFR4 | |
| Acrylic Acid SCHEMBL11252224 | 1.00 | LMNA (1.00) | LMNATSHRALDH1A1HSD17B10FGFR4 | |
| Acrylic Acid SCHEMBL4371336 | 1.00 | — | — | |
| Acrylic Acid SCHEMBL4482 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5721309-A | CROSSLINKABLE ACRYLIC POLYMER; AN AMINO RESIN CROSSLINKING AGENT; A SILICA FLATTING AGENT AND AMINOETHYL-AMINOPROPYL-DIMETHOXY-SILYL-END-BLOCKED POLYDIMETHYLSILOXANE | GENCORP INC. (US) | 1998-02-24 | — | — | US | disclosed |
| US-5594061-A | ACRYLIC LATEX COATINGS WITH REDUCED GLOSS AND SHELF STABILITY | GENCORP INC. (US) | 1997-01-14 | — | — | US | disclosed |