Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8585502 | 0.99 | CNR2 (0.41) | CNR2MEN1ALDH1A1KMT2AALOX5 | |
| SCHEMBL8580858 | 0.95 | CNR2 (0.37) | CNR2ALDH1A1HSD17B10RXFP1PPARA | |
| SCHEMBL8581020 | 0.94 | CNR2 (0.41) | CNR2MEN1ALDH1A1KMT2AALOX5 | |
| SCHEMBL8581804 | 0.92 | CNR2 (0.41) | CNR2MEN1ALDH1A1KMT2AALOX5 | |
| SCHEMBL8578766 | 0.92 | PPARG (0.38) | ALDH1A1HSD17B10PPARAPPARG | |
| SCHEMBL8583499 | 0.89 | CNR2 (0.39) | CNR2MEN1ALDH1A1KMT2AALOX5 | |
| SCHEMBL8580364 | 0.88 | CNR2 (0.37) | CNR2ALDH1A1THRATHRBHSD17B10 | |
| SCHEMBL8583085 | 0.88 | PPARG (0.37) | ALDH1A1KMT2AHSD17B10PPARAPPARG | |
| SCHEMBL8585349 | 0.88 | PPARG (0.37) | ALDH1A1HSD17B10PPARAPPARG | |
| SCHEMBL8583900 | 0.87 | CNR2 (0.40) | CNR2MEN1ALDH1A1KMT2AALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840761-A | Alkylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-11-24 | — | — | US | disclosed |