Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.35 |
| ▸ | GABRE | P78334 | 1/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.35 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.35 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.35 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8585502 | 0.96 | CNR2 (0.41) | CNR2PPARGPPARAKDM4EALDH1A1 | |
| SCHEMBL8580391 | 0.95 | CNR2 (0.40) | CNR2PPARGPPARAALDH1A1HSD17B10 | |
| SCHEMBL8578766 | 0.94 | PPARG (0.38) | PPARGPPARAKDM4EALDH1A1HPGD | |
| SCHEMBL8580364 | 0.93 | CNR2 (0.37) | CNR2KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL8585349 | 0.90 | PPARG (0.37) | PPARGPPARAKDM4EALDH1A1HPGD | |
| SCHEMBL8583085 | 0.90 | PPARG (0.37) | PPARGPPARAKDM4EALDH1A1HPGD | |
| SCHEMBL8581804 | 0.89 | CNR2 (0.41) | CNR2KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL8581020 | 0.88 | CNR2 (0.41) | CNR2PPARGPPARAALDH1A1 | |
| SCHEMBL8578836 | 0.86 | PDGFRB (0.40) | CNR2KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL8583499 | 0.86 | CNR2 (0.39) | CNR2KDM4EALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840761-A | Alkylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-11-24 | — | — | US | disclosed |