Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MGAM | O43451 | 2/20 | 0.39 |
| ▸ | SI | P14410 | 2/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9513 | 0.89 | TSHR (0.50) | TSHRTDP1GAAMGAMSI | |
| SCHEMBL28813485 | 0.87 | MGAM (0.46) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL2221470 | 0.87 | TSHR (0.48) | TSHRTDP1GAAMGAMSI | |
| SCHEMBL1616122 | 0.87 | TSHR (0.48) | TSHRTDP1GAAMGAMSI | |
| SCHEMBL5702374 | 0.87 | TSHR (0.48) | TSHRTDP1GAAMGAMSI | |
| SCHEMBL5134550 | 0.87 | TSHR (0.48) | TSHRTDP1GAAMGAMSI | |
| Acetone SCHEMBL28861611 | 0.87 | TSHR (0.48) | TSHRTDP1GAAMGAMSI | |
| SCHEMBL9248234 | 0.83 | TSHR (0.40) | TSHRTDP1MAPTCACNA1BAPBA1 | |
| Acetoacetic Acid SCHEMBL1318189 | 0.81 | TSHR (0.44) | TSHRTDP1GAAMGAMSI | |
| SCHEMBL7052633 | 0.81 | TSHR (0.44) | TSHRTDP1GAAMGAMSI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9790328-B2 | Polyethercarbonate-polyoxymethylene block copolymers | COVESTRO DEUTSCHLAND AG (DE) | 2017-10-17 | — | — | US | disclosed |
| US-20160130407-A1 | POLYETHERCARBONATE-POLYOXYMETHYLENE BLOCK COPOLYMERS | COVESTRO DEUTSCHLAND AG (DE) | 2016-05-12 | — | — | US | disclosed |
| US-5767199-A | WHICH IS ENDBLOCKED | ROHM AND HASS COMPANY (US) | 1998-06-16 | — | — | US | disclosed |
| EP-0581466-B1 | Compositions containing acetoacetate functional polymer and polyformal | ROHM & HAAS (US) | 1997-04-16 | — | — | EP | disclosed |
| EP-0581466-A2 | Compositions containing acetoacetate functional polymer and polyformal | ROHM AND HAAS COMPANY (US) | 1994-02-02 | — | — | EP | disclosed |