Dimefuron

Dimefuron

SCHEMBL8580864

CN(C)C(=O)Nc1ccc(-n2nc(C(C)(C)C)oc2=O)c(Cl)c1.CN(C)C(=O)Nc1ccc(Cl)c(Cl)c1

nearest known ligand 0.94

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.94
KMT2A Q03164 2/20 0.94
TDP1 Q9NUW8 2/20 0.94
APEX1 P27695 1/20 0.55
PPOX P50336 13/20 0.45
NR1I2 O75469 1/20 0.45
MAPK14 Q16539 1/20 0.40
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
GLA P06280 1/20 0.38
GAA P10253 1/20 0.38
HPGD P15428 1/20 0.38
CNR2 P34972 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimefuron SCHEMBL68325 0.97 MEN1 (1.00) MEN1KMT2ATDP1APEX1PPOX
Dimefuron SCHEMBL9138565 0.97 MEN1 (1.00) MEN1KMT2ATDP1APEX1PPOX
Dimefuron SCHEMBL29436146 0.97 MEN1 (1.00) MEN1KMT2ATDP1APEX1PPOX
Oxadiazon SCHEMBL7582992 0.87 MEN1 (0.71) MEN1KMT2ATDP1APEX1PPOX
Dimefuron SCHEMBL7580496 0.86 MEN1 (0.78) MEN1KMT2ATDP1APEX1PPOX
Dimefuron SCHEMBL7582927 0.83 MEN1 (0.73) MEN1KMT2ATDP1APEX1PPOX
SCHEMBL11848214 0.81 MEN1 (0.72) MEN1KMT2ATDP1PPOXNR1I2
Dimefuron SCHEMBL21300481 0.80 MEN1 (0.69) MEN1KMT2ATDP1PPOXNR1I2
Oxadiazon SCHEMBL7585223 0.80 MEN1 (0.69) MEN1KMT2ATDP1APEX1PPOX
Dimefuron SCHEMBL6477609 0.79 MEN1 (0.67) MEN1KMT2ATDP1PPOXNR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998013341-A1 HYDROXYBENZOPHENONE DERIVATIVES AS HERBICIDES RHONE-POULENC AGRICULTURE LTD. (GB) 1998-04-02 WO disclosed