Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | PPOX | P50336 | 14/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimefuron SCHEMBL9738437 | 1.00 | MEN1 (0.67) | MEN1KMT2ATDP1PPOXNPC1 | |
| Dimefuron SCHEMBL9711354 | 1.00 | MEN1 (0.67) | MEN1KMT2ATDP1PPOXNPC1 | |
| Dimefuron SCHEMBL68325 | 0.82 | MEN1 (1.00) | MEN1KMT2ATDP1PPOXNR1I2 | |
| Dimefuron SCHEMBL29436146 | 0.82 | MEN1 (1.00) | MEN1KMT2ATDP1PPOXNR1I2 | |
| Dimefuron SCHEMBL9138565 | 0.82 | MEN1 (1.00) | MEN1KMT2ATDP1PPOXNR1I2 | |
| Oxadiazon SCHEMBL7579669 | 0.81 | PPOX (0.61) | MEN1KMT2ATDP1PPOXMAPT | |
| Dimethachlor SCHEMBL7579262 | 0.79 | PPOX (0.44) | MEN1KMT2ATDP1PPOXNR1I2 | |
| Dimefuron SCHEMBL8580864 | 0.79 | MEN1 (0.94) | MEN1KMT2ATDP1PPOXNR1I2 | |
| Dimefuron SCHEMBL7580496 | 0.74 | MEN1 (0.78) | MEN1KMT2ATDP1PPOXMAPT | |
| Dimefuron SCHEMBL7582927 | 0.73 | MEN1 (0.73) | MEN1KMT2ATDP1PPOXNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050282707-A1 | Pyridinylisoxazoles and their use as herbicides | BAYER CROPSCIENCE GMBH (DE) | 2005-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050282707-A1 | Pyridinylisoxazoles and their use as herbicides | PRDX1, CYP4X1, PRDX4 | MEN1 3509/4885KMT2A 1815/4885TDP1 1229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.