Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.30 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.30 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.30 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25413351 | 0.68 | LRRK2 (0.40) | LRRK2CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL9963193 | 0.65 | KDM4E (0.35) | KDM4EALDH1A1LRRK2CDK1CCNB1 | |
| SCHEMBL8576327 | 0.64 | KDM4E (0.37) | KDM4EALDH1A1LRRK2CDK1CCNB1 | |
| SCHEMBL2069467 | 0.64 | TLR8 (0.35) | LRRK2CCNA2CDK2CCNA1 | |
| SCHEMBL3390537 | 0.64 | — | — | |
| SCHEMBL8563387 | 0.64 | PDPK1 (0.32) | — | |
| SCHEMBL8564518 | 0.61 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL8382615 | 0.61 | LRRK2 (0.44) | KDM4EALDH1A1LRRK2CDK1CCNB1 | |
| SCHEMBL8578950 | 0.61 | KDM4E (0.33) | KDM4EALDH1A1MAP3K7TAB1 | |
| SCHEMBL8578948 | 0.61 | KDM4E (0.33) | KDM4EALDH1A1MAP3K7TAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664795-A1 | PROPENOIC ACID DERIVATIVES USEFUL AS FUNGICIDES | ZENECA LIMITED (GB) | 1995-08-02 | — | — | EP | claimed |
| WO-1994008968-A1 | PROPENOIC ACID DERIVATIVES USEFUL AS FUNGICIDES | ZENECA LIMITED (GB) | 1994-04-28 | — | — | WO | claimed |
| US-5723473-A | Propenoic acid derivatives useful as fungicides | ZENECA LIMITED (GB) | 1998-03-03 | — | — | US | disclosed |
| EP-0664795-A1 | PROPENOIC ACID DERIVATIVES USEFUL AS FUNGICIDES | ZENECA LIMITED (GB) | 1995-08-02 | — | — | EP | disclosed |
| WO-1994008968-A1 | PROPENOIC ACID DERIVATIVES USEFUL AS FUNGICIDES | ZENECA LIMITED (GB) | 1994-04-28 | — | — | WO | disclosed |