SCHEMBL8581713

CCCCCCCCCCC[C@@H](OC(=O)OCc1ccccc1)[C@H](F)C(=O)NO[C@@H]1O[C@@H]2COC(C)(C)O[C@H]2[C@H](O)[C@H]1O

nearest known ligand 0.34

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	MEN1	O00255	1/20	0.34

▸	ALDH1A1	P00352	1/20	0.34

▸	HPGD	P15428	1/20	0.34

▸	KMT2A	Q03164	1/20	0.34

▸	DAGLA	Q9Y4D2	1/20	0.32

▸	SIRT2	Q8IXJ6	10/20	0.31

▸	SIRT1	Q96EB6	7/20	0.31

▸	SIRT3	Q9NTG7	5/20	0.31

▸	TLR2	O60603	2/20	0.31

▸	YWHAZ	P63104	1/20	0.30

▸	L3MBTL1	Q9Y468	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL8576904	0.84	L3MBTL1 (0.33)	MEN1ALDH1A1HPGDKMT2AL3MBTL1
SCHEMBL8579743	0.84	L3MBTL1 (0.33)	MEN1ALDH1A1HPGDKMT2AL3MBTL1
SCHEMBL8581377	0.75	KMT2A (0.33)	MEN1ALDH1A1HPGDKMT2ADAGLA
SCHEMBL10417606	0.74	L3MBTL1 (0.41)	MEN1ALDH1A1HPGDKMT2AL3MBTL1
SCHEMBL9019034	0.73	L3MBTL1 (0.32)	L3MBTL1
SCHEMBL6807462	0.71	L3MBTL1 (0.40)	L3MBTL1
SCHEMBL6797796	0.71	L3MBTL1 (0.40)	L3MBTL1
SCHEMBL6807464	0.71	L3MBTL1 (0.40)	L3MBTL1
SCHEMBL6797801	0.71	L3MBTL1 (0.40)	L3MBTL1
SCHEMBL10824776	0.71	L3MBTL1 (0.40)	L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-5792840-A	SUBSTITUTED GLUCOPYRANOSYL PHOSPHATES	SANKYO COMPANY, LIMITED (JP)	1998-08-11	—	—	US	disclosed