Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GNPAT | O15228 | 1/20 | 0.33 |
| ▸ | CRAT | P43155 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10308716 | 0.81 | KDM4E (0.46) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL19709025 | 0.81 | KDM4E (0.46) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL8582123 | 0.79 | KDM4E (0.42) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL13188770 | 0.79 | KDM4E (0.68) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL13322047 | 0.79 | MAPT (0.61) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL12963378 | 0.79 | MAPT (0.61) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL2548081 | 0.79 | MAPT (0.50) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL24967258 | 0.78 | MAPT (0.45) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL9521978 | 0.77 | KDM4E (0.48) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL8581718 | 0.77 | MGAM (0.43) | KDM4EMAPTTHRBALOX15NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5705527-A | VASODILATORS AND ANGINA PECTORIS | SANKYO COMPANY, LIMITED (JP) | 1998-01-06 | — | — | US | disclosed |
| EP-0641769-B1 | AMINO ACID DERIVATIVE | SANKYO CO (JP) | 1997-01-29 | — | — | EP | disclosed |
| EP-0641769-A1 | AMINO ACID DERIVATIVE | SANKYO COMPANY LIMITED (JP) | 1995-03-08 | — | — | EP | disclosed |