Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | GNPAT | O15228 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13188770 | 0.79 | KDM4E (0.68) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL497231 | 0.79 | MAPT (0.61) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL6920981 | 0.79 | MAPT (0.61) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL2548081 | 0.79 | MAPT (0.50) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL8582199 | 0.77 | KDM4E (0.48) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL24866254 | 0.76 | SMN1; SMN2 (0.42) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL9521985 | 0.76 | SMN1; SMN2 (0.47) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL4028312 | 0.76 | SMN1; SMN2 (0.42) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL28883929 | 0.76 | KDM4E (0.42) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL1812110 | 0.76 | SMN1; SMN2 (0.42) | KDM4EMAPTTHRBALOX15NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301474-B1 | NEW CYSTEINE DERIVATIVES HAVING EXPECTORANT ACTIVITY | MAGIS FARMACEUTICI S.P.A. (IT) | 1993-09-29 | — | — | EP | disclosed |
| US-4910222-A | Bronchodilator | MAGIS FARMACEUTICI SPA (IT) | 1990-03-20 | — | — | US | disclosed |
| EP-0301474-A2 | New cysteine derivatives having expectorant activity | MAGIS FARMACEUTICI S.P.A. (IT) | 1989-02-01 | — | — | EP | disclosed |