Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GNPAT | O15228 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12963378 | 0.82 | MAPT (0.61) | SMN1; SMN2MAPTKDM4ETHRBALOX15 | |
| SCHEMBL13322047 | 0.82 | MAPT (0.61) | SMN1; SMN2MAPTKDM4ETHRBALOX15 | |
| SCHEMBL11382604 | 0.81 | SMN1; SMN2 (0.45) | SMN1; SMN2MAPTKDM4ETHRBALOX15 | |
| SCHEMBL7436963 | 0.81 | SMN1; SMN2 (0.45) | SMN1; SMN2MAPTKDM4ETHRBALOX15 | |
| SCHEMBL8582124 | 0.80 | SMN1; SMN2 (0.41) | SMN1; SMN2MAPTKDM4ETHRBALOX15 | |
| SCHEMBL8581730 | 0.80 | SMN1; SMN2 (0.48) | SMN1; SMN2MAPTKDM4ETHRBALOX15 | |
| SCHEMBL10308716 | 0.79 | KDM4E (0.46) | SMN1; SMN2MAPTKDM4ETHRBALOX15 | |
| SCHEMBL19709025 | 0.79 | KDM4E (0.46) | SMN1; SMN2MAPTKDM4ETHRBALOX15 | |
| SCHEMBL9521985 | 0.78 | SMN1; SMN2 (0.47) | SMN1; SMN2MAPTKDM4ETHRBALOX15 | |
| SCHEMBL30052623 | 0.78 | SMN1; SMN2 (0.69) | SMN1; SMN2MAPTKDM4ETHRBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5705527-A | VASODILATORS AND ANGINA PECTORIS | SANKYO COMPANY, LIMITED (JP) | 1998-01-06 | — | — | US | disclosed |
| EP-0641769-B1 | AMINO ACID DERIVATIVE | SANKYO CO (JP) | 1997-01-29 | — | — | EP | disclosed |
| EP-0641769-A1 | AMINO ACID DERIVATIVE | SANKYO COMPANY LIMITED (JP) | 1995-03-08 | — | — | EP | disclosed |