Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GNPAT | O15228 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8580669 | 0.85 | SMN1; SMN2 (0.32) | SMN1; SMN2KDM4ERECQLALDH1A1 | |
| SCHEMBL16675994 | 0.85 | MAPT (0.53) | SMN1; SMN2MAPTNFKB1KDM4ETHRB | |
| SCHEMBL16708422 | 0.82 | KDM4E (0.41) | SMN1; SMN2MAPTNFKB1KDM4ETHRB | |
| SCHEMBL8582202 | 0.80 | SMN1; SMN2 (0.47) | SMN1; SMN2MAPTNFKB1KDM4ETHRB | |
| SCHEMBL8582123 | 0.79 | KDM4E (0.42) | SMN1; SMN2MAPTNFKB1KDM4ETHRB | |
| SCHEMBL8582254 | 0.77 | CYP2D6 (0.42) | SMN1; SMN2MAPTNFKB1KDM4ETHRB | |
| SCHEMBL8581730 | 0.74 | SMN1; SMN2 (0.48) | SMN1; SMN2MAPTNFKB1KDM4ETHRB | |
| SCHEMBL30052623 | 0.72 | SMN1; SMN2 (0.69) | SMN1; SMN2MAPTNFKB1KDM4ETHRB | |
| SCHEMBL9521985 | 0.72 | SMN1; SMN2 (0.47) | SMN1; SMN2MAPTNFKB1KDM4ETHRB | |
| SCHEMBL8581719 | 0.71 | MGAM (0.42) | SMN1; SMN2MAPTNFKB1KDM4ETHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5705527-A | VASODILATORS AND ANGINA PECTORIS | SANKYO COMPANY, LIMITED (JP) | 1998-01-06 | — | — | US | disclosed |
| EP-0641769-B1 | AMINO ACID DERIVATIVE | SANKYO CO (JP) | 1997-01-29 | — | — | EP | disclosed |
| EP-0641769-A1 | AMINO ACID DERIVATIVE | SANKYO COMPANY LIMITED (JP) | 1995-03-08 | — | — | EP | disclosed |