Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GLS | O94925 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.39 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8582940 | 1.00 | CYP2C19 (0.46) | CYP2C19TBXAS1FOLH1SMN1; SMN2GLS | |
| SCHEMBL8585706 | 0.95 | TBXAS1 (0.48) | CYP2C19TBXAS1FOLH1SMN1; SMN2GLS | |
| SCHEMBL8585710 | 0.95 | TBXAS1 (0.48) | CYP2C19TBXAS1FOLH1SMN1; SMN2GLS | |
| SCHEMBL8585401 | 0.89 | CYP2C19 (0.49) | CYP2C19TBXAS1SMN1; SMN2GLSGAA | |
| SCHEMBL8585405 | 0.89 | CYP2C19 (0.49) | CYP2C19TBXAS1SMN1; SMN2GLSGAA | |
| SCHEMBL14360139 | 0.81 | TBXAS1 (0.60) | CYP2C19TBXAS1POLBCYP2D6SRC | |
| SCHEMBL455432 | 0.80 | POLB (0.53) | CYP2C19TBXAS1SMN1; SMN2POLB | |
| SCHEMBL9108453 | 0.80 | CYP2C19 (0.53) | CYP2C19SMN1; SMN2GAAPOLBCYP2D6 | |
| Ammonia Solution, Strong SCHEMBL28562956 | 0.80 | TBXAS1 (0.59) | CYP2C19TBXAS1POLBCYP2D6SRC | |
| Ammonia Solution, Strong SCHEMBL28556745 | 0.80 | TBXAS1 (0.59) | CYP2C19TBXAS1POLBCYP2D6SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0603229-B1 | QUINUCLIDINE ESTERS PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PFIZER LTD (GB) | 1998-06-10 | — | — | EP | disclosed |
| US-5543419-A | TREATING CHRONIC OBSTRUCTIVE AIRWAYS DISEASE OR ASTHMA; ANTIMUSCARINIC BRONCHODILATOR AGENTS | PFIZER INC (US) | 1996-08-06 | — | — | US | disclosed |
| EP-0603229-A1 | QUINUCLIDINE ESTERS PROCESS AND INTERMEDIATE FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Pfizer Limited (GB) | 1994-06-29 | — | — | EP | disclosed |
| WO-1993006098-A1 | QUINUCLIDINE ESTERS PROCESS AND INTERMEDIATE FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PFIZER LIMITED (GB) | 1993-04-01 | — | — | WO | disclosed |