Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CMA1 | P23946 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8581247 | 0.92 | KDM4E (0.35) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL8582476 | 0.88 | KDM4E (0.37) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL8581805 | 0.85 | CMA1 (0.43) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL8581010 | 0.85 | KDM4E (0.38) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL8582606 | 0.84 | KDM4E (0.37) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL8585015 | 0.84 | KDM4E (0.37) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL8583897 | 0.83 | KDM4E (0.36) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL8579193 | 0.82 | KDM4E (0.36) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL8581428 | 0.81 | CYP2C19 (0.35) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL8584499 | 0.80 | ALDH1A1 (0.40) | KDM4EALDH1A1MAPTHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840761-A | Alkylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-11-24 | — | — | US | disclosed |