SCHEMBL8583243

SCHEMBL8583243

Nc1cccc2c1OC=CC2

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.34
HPGD P15428 2/20 0.34
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 1/20 0.34
LMNA P02545 1/20 0.34
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
KMT2A Q03164 1/20 0.34
CD44 P16070 1/20 0.32
CYP3A4 P08684 2/20 0.31
TSHR P16473 2/20 0.31
HSD17B10 Q99714 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
PIK3CA P42336 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL277665 0.78
SCHEMBL30779692 0.76 AHR (0.39)
SCHEMBL30779670 0.76 DRD2 (0.30)
SCHEMBL5544996 0.76
SCHEMBL2009439 0.76
SCHEMBL30779735 0.76
SCHEMBL12043458 0.76 CYP1A2 (0.31) ALDH1A1HPGD
SCHEMBL3076683 0.76 BCL2L1 (0.35) ALDH1A1HPGDMEN1LMNAMAPT
SCHEMBL5322268 0.73 PARP1 (0.54) ALDH1A1HPGDKDM4ELMNAGAA
SCHEMBL23258707 0.72 CYP1A2 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5496491-A FOR PHOTORESISTS, AMINE SALT REACTION PRODUCT ASHLAND OIL COMPANY (US) 1996-03-05 US claimed
US-5753601-A STABILIZING THE SOLVENT CLEANING INCLUDING A CORROSION INHIBITOR PYROGALLOL ASHLAND INC (US) 1998-05-19 US disclosed
US-5556482-A POLAR SOLVENT AND BASIC AMINE FOR SUBSTRATES WITH PHOTORESISTS AND PHENOL COMPOUNDS ASHLAND, INC. (US) 1996-09-17 US disclosed
US-5496491-A FOR PHOTORESISTS, AMINE SALT REACTION PRODUCT ASHLAND OIL COMPANY (US) 1996-03-05 US disclosed
US-5417877-A Organic stripping composition ASHLAND INC. (US) 1995-05-23 US disclosed