Acetone

Acetone

SCHEMBL8583301

CC(C)=O.CCC(C)(O)C(=O)O

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.45
TSHR P16473 3/20 0.45
TET2 Q6N021 1/20 0.44
HMGCR P04035 1/20 0.38
CHRM1 P11229 1/20 0.38
TBXA2R P21731 1/20 0.38
ADRA1A P35348 1/20 0.38
CYP2D6 P10635 1/20 0.36
CYP2C19 P33261 1/20 0.36
HIF1A Q16665 1/20 0.36
FFAR3 O14843 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
LMNA P02545 1/20 0.33
MEN1 O00255 1/20 0.33
CYP1A2 P05177 1/20 0.33
THRB P10828 1/20 0.33
KMT2A Q03164 1/20 0.33
LCK P06239 1/20 0.32
FYN P06241 1/20 0.32
KDM4C Q9H3R0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL28944238 0.94 ALDH1A1 (0.45) ALDH1A1TSHRTET2HMGCRCHRM1
SCHEMBL2327762 0.94
SCHEMBL4963143 0.94 TSHR (0.50) ALDH1A1TSHRTET2HMGCRCHRM1
SCHEMBL79613 0.94
SCHEMBL581582 0.94
SCHEMBL28436750 0.92 TSHR (0.47) ALDH1A1TSHRTET2HMGCRCHRM1
SCHEMBL5159386 0.92
SCHEMBL4927191 0.92
SCHEMBL6755733 0.92
Water SCHEMBL15756484 0.92

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5789359-A RINSING, DRYING; WATER AND AIR POLLUTION CONTROL KABUSHIKI KAISHA TOSHIBA (JP) 1998-08-04 US disclosed