Formic Acid

Formic Acid

SCHEMBL8583302

CC(C)(C)OC(=O)C=Cc1ccccc1.O=CO

nearest known ligand 0.51

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.51
EGFR P00533 1/20 0.50
GLA P06280 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
LMNA P02545 4/20 0.49
MAPT P10636 5/20 0.48
ALDH1A1 P00352 4/20 0.48
HDAC3 O15379 2/20 0.48
HDAC4 P56524 2/20 0.48
HDAC1 Q13547 2/20 0.48
HDAC2 Q92769 2/20 0.48
HDAC8 Q9BY41 2/20 0.48
HDAC6 Q9UBN7 2/20 0.48
PLIN1 O60240 2/20 0.48
RECQL P46063 2/20 0.48
PLIN5 Q00G26 2/20 0.48
ABHD5 Q8WTS1 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
TNKS O95271 1/20 0.48
HCAR2 Q8TDS4 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1006098 0.95 GLA (0.55) KMT2AEGFRGLATDP1LMNA
SCHEMBL126771 0.95 GLA (0.55) KMT2AEGFRGLATDP1LMNA
SCHEMBL13845314 0.86 CA12 (0.53) KMT2ALMNAMAPTALDH1A1HDAC1
SCHEMBL4055668 0.86 CA12 (0.53) KMT2ALMNAMAPTALDH1A1HDAC1
SCHEMBL4055672 0.86 CA12 (0.53) KMT2ALMNAMAPTALDH1A1HDAC1
SCHEMBL19244214 0.85 HDAC2 (0.54) KMT2AEGFRGLATDP1LMNA
SCHEMBL19244215 0.85 HDAC2 (0.54) KMT2AEGFRGLATDP1LMNA
SCHEMBL8118316 0.83 HDAC3 (0.53) KMT2AEGFRGLATDP1LMNA
SCHEMBL8104777 0.83 HDAC3 (0.53) KMT2AEGFRGLATDP1LMNA
SCHEMBL17447202 0.83 HDAC3 (0.53) KMT2AEGFRGLATDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0833629-A4 ARYL ACRYLIC ACID DERIVATIVES USEFUL AS PROTEIN TYROSINE PHOSPHATASE INHIBITORS ONTOGEN CORP (US) 1998-09-16 EP disclosed
US-5770620-A ENZYME INHIBITOR AS IMMUNOMODULATORS ONTOGEN CORPORATION (US) 1998-06-23 US disclosed
EP-0833629-A2 ARYL ACRYLIC ACID DERIVATIVES USEFUL AS PROTEIN TYROSINE PHOSPHATASE INHIBITORS ONTOGEN CORPORATION (US) 1998-04-08 EP disclosed
WO-1997008934-A2 ARYL ACRYLIC ACID DERIVATIVES USEFUL AS PROTEIN TYROSINE PHOSPHATASE INHIBITORS ONTOGEN CORPORATION (US) 1997-03-13 WO disclosed