Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 14/20 | 0.83 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12795625 | 1.00 | F10 (0.83) | F10PTGS2USP2ALDH1A1MAPT | |
| SCHEMBL92851 | 1.00 | F10 (0.83) | F10PTGS2USP2ALDH1A1MAPT | |
| SCHEMBL76143 | 0.91 | F10 (1.00) | F10PTGS2MAPT | |
| SCHEMBL77859 | 0.91 | F10 (1.00) | F10PTGS2MAPT | |
| SCHEMBL76892 | 0.91 | F10 (1.00) | F10PTGS2MAPT | |
| SCHEMBL76849 | 0.91 | F10 (1.00) | F10PTGS2MAPT | |
| SCHEMBL76023 | 0.91 | F10 (1.00) | F10PTGS2MAPT | |
| SCHEMBL5956981 | 0.88 | F10 (0.79) | F10MAPT | |
| SCHEMBL3096835 | 0.87 | F10 (0.77) | F10PTGS2MAPT | |
| SCHEMBL77625 | 0.85 | F10 (0.90) | F10PTGS2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129373-B2 | Carbonyl compounds | MERCK PATENT GMBH (DE) | 2012-03-06 | — | — | US | disclosed |
| US-20100256131-A1 | CARBONYL COMPOUNDS | TSAKLAKIDIS CHRISTOS | 2010-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256131-A1 | CARBONYL COMPOUNDS | F2, F11, PDHX | F10 5/4885PTGS2 768/4885USP2 3631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.