SCHEMBL8585010

SCHEMBL8585010

PC(c1ccccc1)c1ccccc1.PC(c1ccccc1)c1ccccc1.PC(c1ccccc1)c1ccccc1.PC(c1ccccc1)c1ccccc1.[Pt]

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.45
F2 P00734 1/20 0.45
TSHR P16473 1/20 0.45
HTR2A P28223 3/20 0.42
HRH1 P35367 3/20 0.42
TAAR1 Q96RJ0 1/20 0.41
TDP1 Q9NUW8 1/20 0.40
CYP2D6 P10635 1/20 0.39
SRC P12931 1/20 0.39
LMNA P02545 2/20 0.38
MTOR P42345 1/20 0.38
RAB9A P51151 1/20 0.38
GRM7 Q14831 1/20 0.38
MAPK1 P28482 1/20 0.38
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
SLC6A3 Q01959 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL628167 0.97 DPP4 (0.47) DPP4F2TSHRHTR2AHRH1
SCHEMBL31378181 0.93 DPP4 (0.45) DPP4F2TSHRHTR2AHRH1
SCHEMBL28698472 0.93 DPP4 (0.45) DPP4F2TSHRHTR2AHRH1
SCHEMBL27552354 0.93 DPP4 (0.45) DPP4F2TSHRHTR2AHRH1
SCHEMBL28859133 0.93 DPP4 (0.45) DPP4F2TSHRHTR2AHRH1
Bromide SCHEMBL9183449 0.93 DPP4 (0.45) DPP4F2TSHRHTR2AHRH1
Hydrochloric Acid SCHEMBL1236348 0.93 TDP1 (0.46) DPP4F2TSHRHTR2AHRH1
SCHEMBL27967470 0.93 DPP4 (0.45) DPP4F2TSHRHTR2AHRH1
Iodide SCHEMBL28347317 0.93 DPP4 (0.45) DPP4F2TSHRHTR2AHRH1
SCHEMBL27551062 0.93 DPP4 (0.45) DPP4F2TSHRHTR2AHRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7258271-A None JP disclosed
JP-10120791-A None JP disclosed
JP-3258789-A None JP disclosed
JP-8239389-A None JP disclosed
JP-H10120791-A SILICON-CONTAINING LADDER POLYMER AND ITS PRODUCTION AGENCY OF IND SCIENCE & TECHNOL 1998-05-12 JP disclosed
JP-H08239389-A SILICON-CONTAINING LADDER POLYMER AND ITS PRODUCTION AGENCY OF IND SCIENCE & TECHNOL 1996-09-17 JP disclosed
JP-H07258271-A BENZO-1,4-DISILACYCLOHEXENE DERIVATIVE AND ITS PRODUCTION AGENCY OF IND SCIENCE & TECHNOL 1995-10-09 JP disclosed
JP-H03258789-A N,1-BISSILYLENAMINE DERIVATIVE AND PRODUCTION THEREOF AGENCY OF IND SCIENCE & TECHNOL 1991-11-19 JP disclosed