Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3869483 | 0.82 | GAA (0.33) | GAA | |
| SCHEMBL27642285 | 0.78 | GAA (0.36) | GAAALDH1A1 | |
| SCHEMBL5802803 | 0.74 | GAA (0.38) | GAAALDH1A1 | |
| SCHEMBL9294210 | 0.73 | — | — | |
| SCHEMBL710561 | 0.71 | — | — | |
| SCHEMBL2687659 | 0.69 | — | — | |
| SCHEMBL30630532 | 0.68 | TRPA1 (0.33) | — | |
| SCHEMBL19114138 | 0.68 | — | — | |
| SCHEMBL7998791 | 0.67 | — | — | |
| SCHEMBL28322776 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4803842-A | MINIMIZES MIGRATION OF TOXINS | CASTLETON, INC. (US) | 1989-02-14 | — | — | US | claimed |
| EP-0281232-A1 | Direct contact cooling and freezing of articles with halocarbon heat transfer liquids | CASTLETON, INC. (US) | 1988-09-07 | — | — | EP | claimed |
| US-4730460-A | FREONS | CASTLETON, INC. (US) | 1988-03-15 | — | — | US | claimed |
| WO-1998042410-A1 | PROCESS FOR EXTRACTION OF HALOCARBON COMPOUNDS FROM HYDROPHOBIC MATRICES | CARR ROBERT (GB) | 1998-10-01 | — | — | WO | disclosed |
| US-4803842-A | MINIMIZES MIGRATION OF TOXINS | CASTLETON, INC. (US) | 1989-02-14 | — | — | US | disclosed |
| EP-0281232-A1 | Direct contact cooling and freezing of articles with halocarbon heat transfer liquids | CASTLETON, INC. (US) | 1988-09-07 | — | — | EP | disclosed |
| US-4730460-A | FREONS | CASTLETON, INC. (US) | 1988-03-15 | — | — | US | disclosed |